{"id":"W2781794792","doi":"10.1128/jvi.00099-17","title":"Evasion of Cytosolic DNA-Stimulated Innate Immune Responses by Herpes Simplex Virus 1","year":2018,"lang":"en","type":"review","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Natural Science Foundation of China","keywords":"Stimulator of interferon genes; Biology; Innate immune system; Herpes simplex virus; Virology; Virus; Pattern recognition receptor; Interferon; DNA virus; RIG-I; Nucleic acid; DNA; Interferon type I; Sting; Signal transducing adaptor protein; Immune system; TLR7; Gene; Immunology; Signal transduction; Toll-like receptor; Cell biology; Genetics; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003096859,0.0005890751,0.0006653608,0.001496666,0.0002122748,0.0006877859,0.0005394889,0.0005975207,0.001983006],"category_scores_gemma":[0.0003350095,0.0001855372,0.0002116846,0.001106692,0.0003235549,0.001002009,0.0005782372,0.001086944,0.001473911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003777317,"about_ca_system_score_gemma":0.0005379351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003119406,"about_ca_topic_score_gemma":0.0004834287,"domain_scores_codex":[0.9999017,0.00001346515,0.00001700957,0.00001774257,0.00003697586,0.00001314692],"domain_scores_gemma":[0.9998527,0.00004569005,0.00003271742,0.000005325708,0.0000374613,0.00002616857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006674751,0.00004810991,0.0002005593,0.01040082,0.00003577288,0.000211811,0.0000600125,0.0002105077,0.005053376,0.003045264,0.02228619,0.9583809],"study_design_scores_gemma":[0.000007353342,0.00006589573,0.0008551921,0.001486017,0.000040802,0.00122679,0.000044219,0.00006096818,0.001444678,0.001176753,0.9935784,0.00001294787],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002628834,0.9979882,0.0001497135,0.000219534,0.00031781,0.000004094928,0.0000137247,0.000009717336,0.001034342],"genre_scores_gemma":[0.001345504,0.9972909,0.0001813094,0.0001144007,0.0003228517,0.000005757952,0.00002827522,0.000001822108,0.0007091632],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001983006,"threshold_uncertainty_score":0.006633878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04015039660394955,"score_gpt":0.3435324761573142,"score_spread":0.3033820795533647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}