{"id":"W2781962409","doi":"10.1097/pas.0000000000001011","title":"SWI/SNF Chromatin-remodeling Complex Status in SMARCB1/INI1-preserved Epithelioid Sarcoma","year":2018,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Epithelioid sarcoma; SMARCB1; SMARCA4; SWI/SNF; Chromatin remodeling; Chromatin; ARID1A; Sarcoma; Immunohistochemistry; Pathology; Biology; Cancer research; Medicine; Gene; Genetics; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004203452,0.0002269808,0.0001923269,0.001333262,0.0001794748,0.0002918382,0.0002190779,0.0002008697,0.0007468196],"category_scores_gemma":[0.0005348093,0.0002309275,0.0001485796,0.0005853789,0.0004519164,0.0002697972,0.0002411528,0.0001239153,0.0001722784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002577456,"about_ca_system_score_gemma":0.0001148595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005587078,"about_ca_topic_score_gemma":0.0007359568,"domain_scores_codex":[0.9997999,0.00003173994,0.00004225666,0.00004639092,0.00003634874,0.00004328346],"domain_scores_gemma":[0.999679,0.00005139147,0.0001159889,0.00004604023,0.00004615061,0.00006152144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001280161,0.00006635825,0.7044756,0.0001555214,0.0001022883,0.009777293,0.0008445869,0.0002701267,0.2739112,0.0001530783,0.00005797223,0.008905909],"study_design_scores_gemma":[0.00002496753,0.0003452445,0.9097002,0.00001968884,0.0001479112,0.0287254,0.0009330032,0.001287493,0.05748812,0.0001810495,0.001132144,0.00001483132],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992896,0.0003037443,0.0001560504,0.000002927637,9.052268e-7,0.000004275053,0.00002124115,0.000003211298,0.0002179456],"genre_scores_gemma":[0.9996583,0.0001291125,0.0001010892,0.000002257455,0.000001134336,0.000002106235,0.0000444373,9.688307e-7,0.00006053382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001333262,"threshold_uncertainty_score":0.002498329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02425408191371725,"score_gpt":0.3002930816378167,"score_spread":0.2760389997240995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}