{"id":"W2781962409","doi":"10.1097/pas.0000000000001011","title":"SWI/SNF Chromatin-remodeling Complex Status in SMARCB1/INI1-preserved Epithelioid Sarcoma","year":2018,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Epithelioid sarcoma; SMARCB1; SMARCA4; SWI/SNF; Chromatin remodeling; Chromatin; ARID1A; Sarcoma; Immunohistochemistry; Pathology; Biology; Cancer research; Medicine; Gene; Genetics; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001027417,0.0001999606,0.000516004,0.000102507,0.0001028547,0.00001982469,0.0005214119,0.00007947115,0.00008225958],"category_scores_gemma":[0.000124005,0.0001366668,0.0002014445,0.0002559873,0.0009471808,0.000007001122,0.0001855718,0.0003160772,0.00001540263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004075487,"about_ca_system_score_gemma":0.0001506435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000942219,"about_ca_topic_score_gemma":0.00004402891,"domain_scores_codex":[0.9977444,0.0005617601,0.0006978856,0.0002618273,0.000236313,0.0004977857],"domain_scores_gemma":[0.998491,0.0001118567,0.0005773218,0.0004275054,0.0002428674,0.0001494263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002894671,0.0002855937,0.01013702,0.00002078849,0.0001298837,0.0003806024,0.000728467,0.002662036,0.9016191,0.00006841421,0.001438923,0.07963448],"study_design_scores_gemma":[0.03794127,0.04690131,0.3626762,0.001003795,0.0005384319,0.03709858,0.01074831,0.06743141,0.1798292,0.01350409,0.2373649,0.004962513],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959024,0.0008518119,0.001250256,0.0009801092,0.0001712512,0.00008248115,0.00001126473,0.000008274265,0.0007421711],"genre_scores_gemma":[0.9950739,0.0008598475,0.002629463,0.0005903133,0.0007600368,0.000003303171,0.000009772019,0.0000285122,0.00004491887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.72179,"threshold_uncertainty_score":0.5573109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02425408191371725,"score_gpt":0.3002930816378167,"score_spread":0.2760389997240995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}