{"id":"W2782113599","doi":"10.1016/j.neubiorev.2018.05.026","title":"Non-invasive biomarkers of fetal brain development reflecting prenatal stress: An integrative multi-scale multi-species perspective on data collection and analysis","year":2018,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Lethbridge; Ottawa Hospital","funders":"","keywords":"Prenatal stress; Epigenome; Metabolome; Bioinformatics; Microbiome; Psychological intervention; Identification (biology); Neuroscience; Medicine; Biomarker; Pregnancy; Biology; Metabolomics; DNA methylation; Offspring; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01383932,0.001404542,0.003437428,0.003063707,0.0004495753,0.003016557,0.002624145,0.002001254,0.001056816],"category_scores_gemma":[0.01280647,0.0005409533,0.0009286167,0.002861683,0.002605177,0.002239021,0.001929395,0.002867182,0.0005518902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001073515,"about_ca_system_score_gemma":0.003951699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002840795,"about_ca_topic_score_gemma":0.004676013,"domain_scores_codex":[0.9970683,0.001036337,0.0002536024,0.0006648462,0.0008628869,0.0001139029],"domain_scores_gemma":[0.9850438,0.01049086,0.0009218514,0.0008566675,0.002428445,0.0002584017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001922095,0.00007906271,0.005405399,0.009204434,0.0004827191,0.0002450084,0.0003784891,0.001009575,0.008845977,0.009599522,0.009279896,0.9552779],"study_design_scores_gemma":[0.00005521828,0.0007252878,0.05239645,0.01913901,0.001893461,0.005311192,0.001698621,0.004150245,0.02328386,0.08934986,0.8015632,0.0004336466],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001579889,0.9580843,0.0339499,0.002860897,0.0008713765,0.00008832466,0.000443219,0.00008976366,0.002032327],"genre_scores_gemma":[0.01261788,0.938302,0.04429718,0.001443392,0.001494272,0.0002495356,0.0005637917,0.00006007183,0.0009718077],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01383932,"threshold_uncertainty_score":0.07319021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3180966517290377,"score_gpt":0.4698179099815726,"score_spread":0.151721258252535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}