{"id":"W2782149754","doi":"10.1016/j.enzmictec.2018.01.004","title":"Improvement in thermostability of xylanase from Geobacillus thermodenitrificans C5 by site directed mutagenesis","year":2018,"lang":"en","type":"article","venue":"Enzyme and Microbial Technology","topic":"Biofuel production and bioconversion","field":"Engineering","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Food and Agricultural Sciences, University of Florida; Institute of Genetics; Higher Education Commision, Pakistan; Higher Education Commission, Pakistan","keywords":"Thermostability; Mutant; Xylanase; Site-directed mutagenesis; Mutagenesis; Biochemistry; Enzyme; Protein engineering; Biology; Thermophile; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006731744,0.0001123284,0.000164045,0.0001185404,0.00002849782,0.000004827043,0.00009195652,0.0002114347,0.0001679846],"category_scores_gemma":[0.00001059922,0.000103292,0.00002197522,0.0002303936,0.0002121048,0.000030948,0.00004450525,0.0001146296,0.00001466052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003492072,"about_ca_system_score_gemma":0.000007680201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005829912,"about_ca_topic_score_gemma":0.00022878,"domain_scores_codex":[0.9993817,0.00001453743,0.0001819121,0.0002231536,0.00003513852,0.0001635799],"domain_scores_gemma":[0.9996902,0.000008628746,0.00002904682,0.0002182006,0.00003033514,0.00002359334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002989969,0.00003534595,0.0006809524,0.00001976247,0.00001624333,9.677384e-7,0.0001496612,6.89703e-7,0.979036,0.000005484157,0.001103618,0.01892143],"study_design_scores_gemma":[0.0004815272,0.00007901835,0.0006323751,0.000008002594,0.000008632498,0.000001632343,0.0001089489,0.0002031312,0.9862584,0.00009135834,0.01201275,0.0001142051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980186,0.0007654866,0.0001294745,0.000246925,0.0001688256,0.0001604224,0.0001454918,0.0002561053,0.0001086804],"genre_scores_gemma":[0.9995098,0.0001594344,0.0001593842,0.00003566357,0.00003637204,0.000005296688,0.00002582613,0.0000115608,0.00005673003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01880722,"threshold_uncertainty_score":0.4212126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004781353006660968,"score_gpt":0.1828441452143909,"score_spread":0.1780627922077299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}