{"id":"W2782208928","doi":"10.1056/nejmoa1703327","title":"Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma","year":2018,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":589,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Calgary","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Scleroderma (fungus); Medicine; Hematopoietic stem cell transplantation; Cyclophosphamide; Immunosuppression; Transplantation; Stem cell; Autologous stem-cell transplantation; CD34; Immunology; Chemotherapy; Surgery; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00243667,0.0004397983,0.0008744052,0.0003524857,0.0002511456,0.000251058,0.0002343138,0.0004154884,0.002646322],"category_scores_gemma":[0.001200086,0.00009369809,0.0004879592,0.0002413545,0.0004934944,0.0001686317,0.000364547,0.0005712422,0.0002802719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001834161,"about_ca_system_score_gemma":0.0006673539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001097965,"about_ca_topic_score_gemma":0.0002076891,"domain_scores_codex":[0.9992509,0.0004707981,0.00009493379,0.00005443703,0.00007490383,0.00005390584],"domain_scores_gemma":[0.9994389,0.0001929042,0.0001411423,0.00004633129,0.00002474761,0.0001558496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4993261,0.02067918,0.03350037,0.003227467,0.001745474,0.0006273702,0.00034932,0.003105671,0.05196692,0.001232109,0.001498966,0.3827411],"study_design_scores_gemma":[0.1519711,0.7709581,0.05268905,0.0005158908,0.0009047795,0.001925547,0.0001152565,0.001944404,0.01104459,0.001296702,0.006601872,0.00003282482],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917567,0.004622554,0.001034282,0.0001847111,0.0001001873,0.001502101,0.00008159257,0.00002166267,0.0006963413],"genre_scores_gemma":[0.9959407,0.001499844,0.001077365,0.0001608267,0.000099274,0.0009390061,0.00008130768,0.00000212786,0.0001996804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002646322,"threshold_uncertainty_score":0.01288646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02730863335350928,"score_gpt":0.2779308613472871,"score_spread":0.2506222279937778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}