{"id":"W2782297377","doi":"10.1093/brain/awx285","title":"Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease","year":2017,"lang":"en","type":"article","venue":"Brain","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":451,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; National Institute on Aging; National Institutes of Health; National Cancer Institute; Servier; Medical Research Council; Hersenstichting; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Genentech; Erasmus Medisch Centrum; Avid Radiopharmaceuticals; Bundesministerium für Bildung und Forschung; ZonMw; Parkinson's UK; Pfizer; Biogen; Huffington Foundation; National Center for Research Resources; Agence Nationale de la Recherche; Wellcome Trust; U.S. Department of Defense; Eli Lilly and Company; Itä-Suomen Yliopisto; Texas Children's Hospital; Institute of Genetics; ACMG Foundation for Genetic and Genomic Medicine; Wellcome; American Parkinson Disease Association; Bristol-Myers Squibb; European Commission; Helsingin Yliopisto; National Institute of General Medical Sciences; H. Lundbeck A/S; Prinses Beatrix Spierfonds; Burroughs Wellcome Fund; American Academy of Neurology; Michael J. Fox Foundation for Parkinson's Research; U.S. Department of Health and Human Services; Helsingin ja Uudenmaan Sairaanhoitopiiri; GlaxoSmithKline; EU Joint Programme – Neurodegenerative Disease Research","keywords":"Glucocerebrosidase; Exome sequencing; Disease; Biology; Genetics; Parkinson's disease; Candidate gene; Lysosomal storage disease; LRRK2; Exome; Gene; Bioinformatics; Medicine; Mutation; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02390754059666908,"score_gpt":0.3146035693480085,"score_spread":0.2906960287513394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}