{"id":"W2782401996","doi":"10.1007/s00262-017-2112-x","title":"Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells","year":2018,"lang":"en","type":"article","venue":"Cancer Immunology Immunotherapy","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Juravinski Cancer Centre; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Ovarian cancer; Cytotoxic T cell; Ascites; Cancer research; Ex vivo; Medicine; Interleukin 21; Immunotherapy; Interleukin 12; Lymphokine-activated killer cell; Immunology; Cancer; Immune system; Biology; In vivo; Internal medicine; T cell; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002067992,0.000720497,0.001168533,0.0003727804,0.0005343627,0.00005279953,0.0006415881,0.0009925023,0.009509109],"category_scores_gemma":[0.00002540244,0.0006804323,0.0002632398,0.000374758,0.00140341,0.00044297,0.000188868,0.0008295284,0.0001776003],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000345668,"about_ca_system_score_gemma":0.0003644548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006373259,"about_ca_topic_score_gemma":0.0003525085,"domain_scores_codex":[0.9964144,0.0005051351,0.001068256,0.0009867128,0.0001201875,0.0009053698],"domain_scores_gemma":[0.9971774,0.00022509,0.001120743,0.0008737897,0.0005516668,0.00005131045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00269908,0.000570969,0.01505088,0.00004168543,0.003065693,0.000003631158,0.001674368,0.00000632805,0.9515017,0.00002094373,0.005033023,0.02033165],"study_design_scores_gemma":[0.008842842,0.0006796995,0.08383433,0.0003017363,0.0001899514,0.000008489192,0.0002658652,0.000007378574,0.8385329,0.00003816803,0.06666475,0.0006338701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9257768,0.05689281,0.00007866906,0.0003596185,0.01488649,0.0007711412,0.0004809851,0.0001825065,0.0005709824],"genre_scores_gemma":[0.9459732,0.04364854,0.0001159796,0.003161515,0.0002699069,0.0003962738,0.0002659054,0.000139174,0.006029463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1129688,"threshold_uncertainty_score":0.9995647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008768739890157445,"score_gpt":0.2335281708471058,"score_spread":0.2247594309569484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}