{"id":"W2782597408","doi":"10.1373/clinchem.2017.282319","title":"Resolution of Spurious Immunonephelometric IgG Subclass Measurement Discrepancies by LC-MS/MS","year":2018,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary; Vancouver General Hospital; University of British Columbia; St. Paul's Hospital","funders":"","keywords":"Subclass; Chemistry; Immunoglobulin G; Antibody; Chromatography; Heavy chain; Immunoglobulin heavy chain; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001450465,0.0002539128,0.0005420991,0.00004992432,0.0002584821,0.00001430068,0.000559133,0.0005486656,0.0009060363],"category_scores_gemma":[0.0014678,0.0002307195,0.0003227262,0.0004369794,0.001678205,0.00007463628,0.0001860906,0.0005402152,0.0003613252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007498023,"about_ca_system_score_gemma":0.0001543959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001152456,"about_ca_topic_score_gemma":0.000002228939,"domain_scores_codex":[0.9975803,0.0001621011,0.001098631,0.0004874901,0.0001514415,0.0005200398],"domain_scores_gemma":[0.9982761,0.0002173707,0.0004268408,0.0007217254,0.0003396489,0.00001827442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003554932,0.001003101,0.003443724,0.00008562432,0.0002576281,0.000001246803,0.000118152,6.298426e-7,0.9757733,0.00005520025,0.00975995,0.009145941],"study_design_scores_gemma":[0.002401763,0.0003931799,0.01351246,0.0001095044,0.000101099,0.00001460893,0.0002844604,0.000009995819,0.6995821,0.0001400331,0.2830478,0.0004030294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9302835,0.05679391,0.000204607,0.0003031625,0.001037019,0.0001680477,0.00005354449,0.0001026537,0.01105351],"genre_scores_gemma":[0.9954149,0.0004382503,0.00002113483,0.00009122161,0.00003305026,0.00001455271,0.0001376578,0.00002130609,0.003827984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2761912,"threshold_uncertainty_score":0.9920462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02979810800444038,"score_gpt":0.2884397024266853,"score_spread":0.2586415944222449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}