{"id":"W2782629689","doi":"10.1152/ajplung.00326.2017","title":"Transient stretch induces cytoskeletal fluidization through the severing action of cofilin","year":2018,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Cofilin; Cytoskeleton; Actin; Cell biology; Chemistry; Biophysics; Gene knockdown; Mechanosensitive channels; Cell; Actin cytoskeleton; Biology; Biochemistry; Ion channel","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007694326,0.0002352665,0.0001693759,0.0001003524,0.0002123447,0.000245974,0.0001394414,0.0002436126,0.001727256],"category_scores_gemma":[0.00009984944,0.0001542838,0.0002242865,0.00007435139,0.0002560167,0.0001953919,0.0002912992,0.0005044835,0.0002453466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002915693,"about_ca_system_score_gemma":0.0001725679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009746431,"about_ca_topic_score_gemma":0.001557159,"domain_scores_codex":[0.9999039,0.000008279597,0.000005734037,0.000022933,0.00002344366,0.00003567817],"domain_scores_gemma":[0.9999393,0.000009666703,0.00001646625,0.000007847425,0.000004932139,0.00002187694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004223326,0.00001076353,0.0001807319,0.00001500387,0.000001823604,0.00002020729,0.000006594212,0.00002475058,0.9991967,0.00002480051,0.00002520339,0.0004512545],"study_design_scores_gemma":[0.00002903546,0.0004606409,0.04156347,0.000008999313,0.000009447266,0.0001948106,0.00008761504,0.00185517,0.9540976,0.00006346307,0.001623562,0.00000621034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995369,0.0006648604,0.002223411,0.0001493881,0.00002989666,0.00003060773,0.0002037314,0.00008444057,0.001244627],"genre_scores_gemma":[0.9981907,0.0002423248,0.0005733498,0.00004608814,0.000006405778,0.00002932389,0.0001815251,0.000008074881,0.0007221627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001727256,"threshold_uncertainty_score":0.005778253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007630031835389614,"score_gpt":0.2590297348715327,"score_spread":0.2513997030361431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}