{"id":"W2782830751","doi":"10.1021/acs.jproteome.7b00817","title":"Proteomic Profiling of <i>Leishmania donovani</i> Promastigote Subcellular Organelles","year":2018,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Genome British Columbia; University of Victoria; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Warren Y. Soper Charitable Trust; Fondation De Famille Alvin Segal; Jewish General Hospital; Leading Edge Endowment Fund; Genome British Columbia; Institute of Infection and Immunity; Segal Family Foundation; Genome Canada; Wellcome Trust; McGill University","keywords":"Proteome; Organelle; Cell fractionation; Subcellular localization; Leishmania donovani; Leishmania; Biology; Proteomics; Cell biology; Immunoelectron microscopy; Leishmania mexicana; Biochemistry; Computational biology; Leishmaniasis; Parasite hosting; Membrane; Cytoplasm; Visceral leishmaniasis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001290859,0.0002306494,0.0002017115,0.0004022827,0.0002686703,0.000371129,0.0001287378,0.0001648684,0.0003035754],"category_scores_gemma":[0.0001435395,0.0001116898,0.0001630491,0.0004062992,0.0001246815,0.0002192751,0.0002041231,0.0002135943,0.0002224594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002025815,"about_ca_system_score_gemma":0.0002508862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000933868,"about_ca_topic_score_gemma":0.002019905,"domain_scores_codex":[0.9999453,0.00000750232,0.00000442965,0.00001664701,0.00001362118,0.0000125315],"domain_scores_gemma":[0.9999521,0.000006641043,0.000009947866,0.000003332671,0.00001721051,0.00001091714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002555899,0.000004912856,0.0004527314,0.00004120999,0.000003056241,0.00004414508,0.00001723388,0.00002728169,0.9987025,0.00003286828,0.00002461186,0.0006237908],"study_design_scores_gemma":[0.0000150373,0.0002570724,0.06931971,0.0000279657,0.00006143744,0.001596431,0.0004158462,0.001891726,0.9184113,0.000222732,0.007763511,0.0000172564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990542,0.001555099,0.004834477,0.0001139502,0.000009984892,0.00003858419,0.00139974,0.00007083729,0.001435243],"genre_scores_gemma":[0.9790284,0.002776536,0.01247293,0.0001447397,0.00001064926,0.00004943168,0.003924272,0.00003911863,0.001554034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000933868,"threshold_uncertainty_score":0.001856923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09064934389339493,"score_gpt":0.3940551105221761,"score_spread":0.3034057666287812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}