{"id":"W2782868584","doi":"10.1186/s12883-018-1014-7","title":"Rationale and design of the CAROLINA® - cognition substudy: a randomised controlled trial on cognitive outcomes of linagliptin versus glimepiride in patients with type 2 diabetes mellitus","year":2018,"lang":"en","type":"article","venue":"BMC Neurology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Eli Lilly and Company","keywords":"Linagliptin; Medicine; Cognitive decline; Glimepiride; Dementia; Internal medicine; Type 2 diabetes; Type 2 Diabetes Mellitus; Cognition; Randomized controlled trial; Diabetes mellitus; Physical therapy; Psychiatry; Endocrinology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001963151,0.0001148753,0.0004930004,0.00009352515,0.00002565524,0.000002371282,0.00003743864,0.00004649637,0.00001610304],"category_scores_gemma":[0.0006350669,0.00006727943,0.00005181457,0.0001087786,0.0001893975,0.00002270822,0.00002252384,0.00005817728,0.000002689771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006878032,"about_ca_system_score_gemma":0.00004391989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003214627,"about_ca_topic_score_gemma":0.00002524803,"domain_scores_codex":[0.9990055,0.0002759199,0.0002550813,0.0001713928,0.0001611194,0.0001309942],"domain_scores_gemma":[0.9980542,0.001442203,0.0001848649,0.0001139337,0.0001801958,0.00002458699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7429686,0.0006344125,0.2556941,0.00001957275,0.000286055,0.000001125473,0.0000797597,0.000007513795,0.00004784098,0.00002766752,0.00001216974,0.0002212358],"study_design_scores_gemma":[0.5996837,0.01386792,0.3848723,0.00002078337,0.0005574535,4.375453e-8,0.000007911337,0.00006291088,0.0008450847,0.00004064554,0.000003675846,0.0000375249],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933589,0.00004421346,0.00001463495,0.0000983227,0.0002389472,0.006003885,0.000005786015,0.000007154255,0.0002282221],"genre_scores_gemma":[0.9993755,0.000009844417,0.00005481276,0.0002569335,0.00002880935,0.0002184048,0.00001719752,0.000009571935,0.00002898289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1432848,"threshold_uncertainty_score":0.2743576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02628531293959732,"score_gpt":0.2589053458229476,"score_spread":0.2326200328833502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}