{"id":"W2782977601","doi":"10.3762/bjoc.14.6","title":"Stereochemical outcomes of C–F activation reactions of benzyl fluoride","year":2018,"lang":"en","type":"article","venue":"Beilstein Journal of Organic Chemistry","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; PROTEO","funders":"Engineering and Physical Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; University of St Andrews; Centre in Green Chemistry and Catalysis; Swansea University; Fonds de recherche du Québec – Nature et technologies; Université Laval","keywords":"Chemistry; Enantiopure drug; Nucleophile; Isotopomers; Reactivity (psychology); Hydrogen bond; Medicinal chemistry; Halogen; Fluoride; Stereochemistry; Catalysis; Organic chemistry; Molecule; Enantioselective synthesis; Inorganic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005785461,0.0002412765,0.0005834712,0.00006111815,0.00006752418,0.000006670883,0.0005517033,0.0004440746,0.008324389],"category_scores_gemma":[0.001176942,0.0002308602,0.0002334617,0.000316964,0.0004219445,0.0001409829,0.0001298582,0.0008949272,0.00001659371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001645673,"about_ca_system_score_gemma":0.0003561064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003517795,"about_ca_topic_score_gemma":5.666917e-7,"domain_scores_codex":[0.9978089,0.0000627675,0.001287281,0.0001999766,0.0003670048,0.0002740732],"domain_scores_gemma":[0.9968007,0.0005062926,0.00137989,0.0003630101,0.0007370692,0.0002130622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002554153,0.0004139162,0.02285608,0.0002420385,0.000409493,0.000009803049,0.0002396742,0.000003415862,0.972325,0.00001296894,0.002622544,0.0006096676],"study_design_scores_gemma":[0.001731391,0.00009704838,0.001671217,0.00009648115,0.0002139768,0.0002822385,0.0002709417,0.00001724552,0.9877105,0.0001319173,0.007601697,0.0001753109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995756,0.0001253397,0.0001398412,0.0007218632,0.0004767242,0.00007406215,0.00002904685,0.0000209814,0.002656181],"genre_scores_gemma":[0.9968367,0.00005175509,0.0005980364,0.00007540011,0.0008302412,0.000001450432,0.000009322541,0.00003566443,0.001561417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02118486,"threshold_uncertainty_score":0.9925821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05950283649316218,"score_gpt":0.3949715185824211,"score_spread":0.3354686820892589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}