{"id":"W2783190828","doi":"10.1002/eji.201747351","title":"Treatment of MCPT8<sup>DTR</sup> mice with high‐ or low‐dose diphtheria toxin leads to differential depletion of basophils and granulocyte‐macrophage progenitors","year":2018,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Université de Strasbourg; Institute of Genetics; Institut National de la Santé et de la Recherche Médicale; National Institutes of Health; Freiburg Institute for Advanced Studies, Albert-Ludwigs-Universität Freiburg; Agence Nationale de la Recherche","keywords":"Diphtheria toxin; Biology; Immunology; Granulocyte; Basophil; Fluorescein isothiocyanate; Progenitor cell; Macrophage; Haematopoiesis; Toxin; Stem cell; Cell biology; Microbiology; Antibody; In vitro; Immunoglobulin E; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003145015,0.0009319934,0.0004432121,0.0007263519,0.0002129909,0.000375519,0.0004077439,0.000739419,0.003149572],"category_scores_gemma":[0.0001713415,0.0003606588,0.0004082209,0.0001925034,0.0004718843,0.000311163,0.0002674367,0.001857301,0.000922664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003912223,"about_ca_system_score_gemma":0.0001628406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004833249,"about_ca_topic_score_gemma":0.0006924529,"domain_scores_codex":[0.9994505,0.00009233413,0.00008383851,0.0001227862,0.0001239893,0.0001264618],"domain_scores_gemma":[0.9994817,0.00009518029,0.0001896283,0.00005823412,0.00002806982,0.0001470168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001948344,0.00004768756,0.00008558428,0.00002188697,0.000003106954,0.00005615608,0.000009050133,0.00002584591,0.9991992,0.00005523756,0.00002996628,0.000271395],"study_design_scores_gemma":[0.0000540074,0.0007611206,0.003847932,0.00001215973,0.00001720113,0.0003922074,0.00002710312,0.0006893236,0.9928936,0.00003116986,0.00126799,0.000006141247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912349,0.0008935417,0.003298077,0.000226792,0.00005495386,0.0001224791,0.002441385,0.0002581908,0.001469636],"genre_scores_gemma":[0.9831791,0.0006832155,0.006077578,0.0002308804,0.00004944687,0.0002728371,0.002043191,0.0002134533,0.007250361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003149572,"threshold_uncertainty_score":0.01053637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01037368421000728,"score_gpt":0.2219165810972829,"score_spread":0.2115428968872756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}