{"id":"W2783466784","doi":"10.1136/annrheumdis-2017-212478","title":"Efficacy and safety of tregalizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase IIb, randomised, placebo-controlled trial","year":2018,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital","funders":"Biotest; AbbVie","keywords":"Medicine; Rheumatoid arthritis; Methotrexate; Placebo; Antirheumatic Agents; Internal medicine; Physical therapy; Randomized controlled trial; Clinical trial; Alternative medicine; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003358118,0.001972307,0.004991703,0.0005967706,0.0006932829,0.0015828,0.001146339,0.003297103,0.004070569],"category_scores_gemma":[0.003264145,0.001067244,0.003491188,0.0006928318,0.001869588,0.001468732,0.0004149442,0.003305233,0.0009453786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008240792,"about_ca_system_score_gemma":0.0007582696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008586752,"about_ca_topic_score_gemma":0.001212988,"domain_scores_codex":[0.9984033,0.0008121338,0.0001579285,0.0002791737,0.0001324246,0.0002150761],"domain_scores_gemma":[0.9980477,0.0007880199,0.0004984468,0.000181674,0.0001074935,0.0003767436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9826178,0.001888967,0.001046664,0.0007122968,0.001706872,0.00005112973,0.00004896391,0.0001457273,0.002330135,0.00004294212,0.0002380059,0.009170492],"study_design_scores_gemma":[0.9579468,0.03648451,0.003263604,0.00004887773,0.001323448,0.00006355773,0.00002325702,0.0001784747,0.0002490064,0.00007902311,0.0003214908,0.00001788411],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778799,0.01692338,0.0005453301,0.000690459,0.000465555,0.001228598,0.0005935195,0.00008029908,0.00159295],"genre_scores_gemma":[0.9918374,0.003710605,0.0007404463,0.0008188715,0.0004791354,0.0008692971,0.0006482956,0.0000175333,0.0008784396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004991703,"threshold_uncertainty_score":0.01775962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02106548231235181,"score_gpt":0.3265432012661672,"score_spread":0.3054777189538154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}