{"id":"W2783595944","doi":"10.1089/hum.2017.201","title":"Transducing Airway Basal Cells with a Helper-Dependent Adenoviral Vector for Lung Gene Therapy","year":2018,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Genetic enhancement; Transduction (biophysics); Gene delivery; Cystic fibrosis; Viral vector; Biology; Transgene; Airway; Immunology; Cell biology; Pathology; Gene; Medicine; Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004740768,0.0002855656,0.0002927595,0.0002425837,0.0001849136,0.000407673,0.0002296041,0.0003616545,0.001269594],"category_scores_gemma":[0.0001486741,0.0001592687,0.0002499236,0.0001242601,0.0004044584,0.0002633109,0.0002481283,0.0008659043,0.0006063929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002119621,"about_ca_system_score_gemma":0.0003280468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004387262,"about_ca_topic_score_gemma":0.0005514948,"domain_scores_codex":[0.9998025,0.00003732263,0.00001851057,0.00003611505,0.00007462359,0.00003099175],"domain_scores_gemma":[0.9999077,0.00002999108,0.00001653361,0.00002034002,0.000008277899,0.00001715453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001925712,0.00001909649,0.0001279356,0.00004001771,0.000002579657,0.00003931525,0.00002127626,0.00003343009,0.9969482,0.0002327609,0.0000428811,0.002473238],"study_design_scores_gemma":[0.00002904168,0.0005256634,0.001416647,0.00002257127,0.00002675389,0.0005296278,0.00004162458,0.001106596,0.9821473,0.0001574375,0.01398791,0.000008689064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8372844,0.008096842,0.1437895,0.0004887803,0.0004648038,0.0008677979,0.0008306844,0.0006790698,0.007498171],"genre_scores_gemma":[0.904493,0.006652174,0.08000304,0.0001821358,0.00006934028,0.0002353962,0.001039064,0.0000632919,0.007262598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001269594,"threshold_uncertainty_score":0.004247189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07000342895297403,"score_gpt":0.3722085776113632,"score_spread":0.3022051486583892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}