{"id":"W2783808229","doi":"10.1038/s41598-017-18429-0","title":"Phenotype and Functional Features of Human Telomerase Reverse Transcriptase Immortalized Human Airway Smooth Muscle Cells from Asthmatic and Non-Asthmatic Donors","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Medical Research Council; Rijksuniversiteit Groningen; Universitair Medisch Centrum Groningen; National Health and Medical Research Council; European Commission; European Respiratory Society","keywords":"Telomerase reverse transcriptase; Immunology; Immortalised cell line; Extracellular matrix; Telomerase; Cell culture; Inflammation; Eotaxin; Fibronectin; Biology; Cell biology; Medicine; Chemokine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006554661,0.0001908341,0.00024717,0.0001418218,0.0003887452,0.0001115804,0.00009895937,0.0001018189,0.0003896962],"category_scores_gemma":[0.00009284381,0.0001764516,0.00007698499,0.0001855971,0.0008774595,0.0000177441,0.000117442,0.0001028655,0.000005067743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001521671,"about_ca_system_score_gemma":0.00007977477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005427087,"about_ca_topic_score_gemma":0.0004670988,"domain_scores_codex":[0.9980792,0.0000813956,0.000406113,0.0007951921,0.0003659327,0.0002721774],"domain_scores_gemma":[0.9987087,0.00001783758,0.000210145,0.0006735988,0.0002161157,0.0001736352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003155097,0.00007099599,0.003224898,0.00006355161,0.00004265027,0.00003398992,0.0003867208,5.963369e-7,0.9906386,0.000009717927,0.004436269,0.001060503],"study_design_scores_gemma":[0.0007381823,0.0003881655,0.1651543,0.0000664944,0.00005253997,0.00001996185,0.0002584737,0.00001382806,0.8258888,0.001259054,0.00586721,0.000293095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979297,0.000367691,0.0000997819,0.00002572263,0.0007497545,0.0003709954,0.00003587015,0.00001083684,0.0004096807],"genre_scores_gemma":[0.9980845,0.000006713639,0.0002542222,0.00001893119,0.0001215864,0.00001649127,0.000265161,0.00002217967,0.001210204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1647498,"threshold_uncertainty_score":0.7195489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01421060840966872,"score_gpt":0.2675041990958267,"score_spread":0.253293590686158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}