{"id":"W2783886930","doi":"10.3390/microorganisms6010003","title":"Pichia pastoris is a Suitable Host for the Heterologous Expression of Predicted Class I and Class II Hydrophobins for Discovery, Study, and Application in Biotechnology","year":2018,"lang":"en","type":"article","venue":"Microorganisms","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Pichia pastoris; Heterologous; Computational biology; Biology; Heterologous expression; Pichia; Host (biology); Microbiology; Gene; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001405074,0.0001136879,0.0002243565,0.00006541475,0.000230832,0.00000716482,0.0001050545,0.0002344654,0.000003297923],"category_scores_gemma":[0.00005346098,0.00007785465,0.00002454034,0.0001373523,0.0003346912,0.00003639627,0.0001192163,0.000120812,7.514608e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002437088,"about_ca_system_score_gemma":0.00002495728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006613548,"about_ca_topic_score_gemma":0.0001570902,"domain_scores_codex":[0.999234,0.00001746484,0.0002142988,0.0003167888,0.00004018687,0.0001772883],"domain_scores_gemma":[0.9993421,0.000171627,0.00009448772,0.0003053543,0.00005767331,0.00002877047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002466829,0.0003037723,0.01656134,0.00003302883,0.00002592017,1.405861e-7,0.0008926562,9.742992e-8,0.9804169,0.0001304475,0.0008124355,0.0005765703],"study_design_scores_gemma":[0.002792352,0.003257038,0.04946227,0.00002677802,0.0001132761,0.00001481195,0.0009169147,0.0003475587,0.9313422,0.0003609615,0.01126593,0.00009984511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987572,0.0002680645,0.006047514,0.003568941,0.0000520603,0.002203646,0.0002510735,0.0000298747,0.000006872166],"genre_scores_gemma":[0.9981578,0.00006146786,0.00080168,0.0003197657,0.00006601863,0.0003842151,0.00005044709,0.00001593362,0.0001426704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04907465,"threshold_uncertainty_score":0.317482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007549177739957581,"score_gpt":0.2538407622940544,"score_spread":0.2462915845540969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}