{"id":"W2784021290","doi":"10.1093/hmg/ddx429","title":"Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics","year":2018,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Birth, Development, and Health","field":"Medicine","cited_by":198,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cégep de Chicoutimi; Université de Sherbrooke; Centre Hospitalier Universitaire de Sherbrooke","funders":"FP7 Ideas: European Research Council; European Social Fund; National Institute of Environmental Health Sciences; National Human Genome Research Institute; National Institute for Health and Care Research; National Institute on Aging; European Foundation for the Study of Diabetes; Fonds de Recherche du Québec - Santé; Institute of Genetics; National Health and Medical Research Council; Novo Nordisk Fonden; ZonMw; European Regional Development Fund; H2020 European Research Council; Economic and Social Research Council; European Commission; Diabetes Research and Wellness Foundation; Universitetet i Bergen; Novo Nordisk; National Institute on Handicapped Research; Canadian Diabetes Association; Helse Vest; British Heart Foundation; NIHR Oxford Biomedical Research Centre; Wellcome Trust; Medical Research Council; Università degli Studi di Ferrara; Canadian Institutes of Health Research; National Institute of Diabetes and Digestive and Kidney Diseases; Wellcome","keywords":"Biology; Offspring; Genome-wide association study; Genetics; Genetic association; Single-nucleotide polymorphism; Pregnancy; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003592061,0.0002793209,0.0006269592,0.0003620401,0.0001052918,0.0000325669,0.0001863877,0.000191235,0.00002440478],"category_scores_gemma":[0.0000456446,0.000280434,0.00005602654,0.0001946073,0.0001096861,0.00002904135,0.0002017597,0.0002055454,0.000005288718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003075594,"about_ca_system_score_gemma":0.0001157587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001054789,"about_ca_topic_score_gemma":0.0005856371,"domain_scores_codex":[0.9974628,0.0001208828,0.0006834359,0.0004483562,0.000807924,0.0004766138],"domain_scores_gemma":[0.9985198,0.00005172271,0.0005844849,0.000394643,0.0002666552,0.0001826945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006270935,0.000492909,0.8866351,0.0006322145,0.0002525858,0.00007667432,0.007567133,0.00002030816,0.1040807,0.00006272849,0.000007653298,0.0001092323],"study_design_scores_gemma":[0.003460321,0.001024478,0.9204439,0.0001459851,0.0001090075,0.000006800898,0.000801831,0.00005052008,0.07308932,0.00061998,0.00003231579,0.0002155382],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969301,0.001410601,0.0003701836,0.00003309561,0.0001529453,0.0009874315,0.000009152617,0.00001831593,0.00008820185],"genre_scores_gemma":[0.9948774,0.003755176,0.0009751651,0.0001271897,0.00009158579,0.0000317556,0.000008944227,0.00005288871,0.00007989053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03380878,"threshold_uncertainty_score":0.9999648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01343731617197887,"score_gpt":0.2557922222665434,"score_spread":0.2423549060945645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}