{"id":"W2784110578","doi":"10.3390/pharmaceutics10010006","title":"Regulation of Hepatic UGT2B15 by Methylation in Adults of Asian Descent","year":2018,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute on Minority Health and Health Disparities; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Methylation; Chemistry; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002725705,0.00008246451,0.0001135299,0.00005870128,0.00001696355,0.000002828163,0.00007803777,0.00008845036,0.00002016266],"category_scores_gemma":[0.00006990723,0.00008730878,0.00003747994,0.0001381774,0.00007448874,0.000003767694,0.00003209312,0.00004272953,0.000001769395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001379752,"about_ca_system_score_gemma":0.00002820572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002629184,"about_ca_topic_score_gemma":0.00003294209,"domain_scores_codex":[0.9991961,0.0000787443,0.0003228722,0.0001543989,0.0001324015,0.0001154923],"domain_scores_gemma":[0.9994445,0.00001146624,0.0001800331,0.0001684148,0.0001577709,0.00003781205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001213037,0.0000794486,0.02749455,0.00005387806,0.00001344549,5.570115e-8,0.000168393,0.00007642379,0.9545671,0.00003469089,0.00004255136,0.0173482],"study_design_scores_gemma":[0.000674616,0.0001889576,0.02130484,0.00003175899,0.00001644683,1.702548e-7,0.00002510802,0.003996853,0.9707124,0.0002298425,0.002737574,0.00008145659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923687,0.001160356,0.005195114,0.00004968811,0.0001029641,0.0001808313,0.00001631772,0.000003233668,0.000922781],"genre_scores_gemma":[0.9980599,0.0004668574,0.001220225,0.00002096925,0.00007397147,0.000003982772,0.0001029974,0.00001190646,0.00003914818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01726675,"threshold_uncertainty_score":0.3560349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01964557904586529,"score_gpt":0.3222475955392643,"score_spread":0.302602016493399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}