{"id":"W2784247731","doi":"10.1038/s41598-018-19704-4","title":"Dexamethasone induced miR-155 up-regulation in differentiating 3T3-L1 preadipocytes does not affect adipogenesis","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"Adipogenesis; Endocrinology; Internal medicine; Rosiglitazone; Glucocorticoid; Glucocorticoid receptor; Dexamethasone; Mifepristone; 3T3-L1; microRNA; Endogeny; Downregulation and upregulation; Biology; Chemistry; Receptor; Medicine; Adipose tissue; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002246067,0.0004386722,0.000596565,0.0003173584,0.0003089916,0.0005959802,0.0002226699,0.0004661501,0.003447794],"category_scores_gemma":[0.0001976988,0.0002232194,0.0005974675,0.0003116374,0.0003338655,0.0002442291,0.0002881577,0.001550957,0.00123885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004398224,"about_ca_system_score_gemma":0.0004491638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001087571,"about_ca_topic_score_gemma":0.002075135,"domain_scores_codex":[0.9995067,0.00006000766,0.00007036714,0.0001322624,0.0001456044,0.00008497437],"domain_scores_gemma":[0.9998211,0.00004399768,0.00003938721,0.00002443488,0.00002651006,0.00004468952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001704806,0.0000394175,0.0001236377,0.00005534063,0.000006263363,0.00005474787,0.00002445925,0.00001744257,0.9986236,0.00007044389,0.00006052805,0.0007536366],"study_design_scores_gemma":[0.0000332725,0.0004034156,0.005299824,0.00001369216,0.00002759703,0.0001954706,0.00007684183,0.0002644338,0.986827,0.00005080733,0.006798065,0.00000953263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9645215,0.01359625,0.00647768,0.0005560882,0.0006680327,0.0002135389,0.005158503,0.0002991005,0.008509306],"genre_scores_gemma":[0.9694272,0.004697313,0.008745816,0.0005808181,0.00006231943,0.000324387,0.0053834,0.0001020513,0.01067671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003447794,"threshold_uncertainty_score":0.01153404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01617657214323701,"score_gpt":0.2683190668146473,"score_spread":0.2521424946714103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}