{"id":"W2784453912","doi":"10.3390/v10010012","title":"Sustained IFN-I Expression during Established Persistent Viral Infection: A “Bad Seed” for Protective Immunity","year":2017,"lang":"en","type":"review","venue":"Viruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Lymphocytic choriomeningitis; Immunology; Biology; Immune system; Immunity; Virology; Simian immunodeficiency virus; Innate immune system; Virus; Chronic infection; clone (Java method); Viral pathogenesis; Viral replication; CD8; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0003143205,0.000516516,0.001316158,0.0003206292,0.001491881,0.0001286901,0.0004300414,0.0006351834,0.0002216538],"category_scores_gemma":[0.0006085476,0.0003709867,0.000915343,0.00009658436,0.000247242,0.0002739617,0.0004796621,0.0007338256,0.0006116067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004219832,"about_ca_system_score_gemma":0.0004914217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007349037,"about_ca_topic_score_gemma":0.00007275508,"domain_scores_codex":[0.9976686,0.0006021067,0.0004248619,0.0005560389,0.00006581125,0.0006825539],"domain_scores_gemma":[0.998225,0.0002621407,0.0004302029,0.0008443042,0.0001757862,0.00006252478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001546643,0.001349779,0.0001789722,0.02406837,0.005958333,0.00009107711,0.0006171035,9.843297e-7,0.004938845,0.00005690026,0.002996506,0.9581965],"study_design_scores_gemma":[0.001821017,0.0006307131,0.0001437365,0.004024918,0.0005767401,0.00007981957,0.00007006272,7.127228e-8,0.002304534,0.00002318296,0.989939,0.0003861978],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001185218,0.992876,0.00002592849,0.00001257022,0.00045377,0.003996633,0.0007454042,0.0001336128,0.0005708655],"genre_scores_gemma":[0.001735229,0.9883683,0.00003193721,0.000007640747,0.0001390745,0.00361445,0.000861932,0.00006907048,0.005172365],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9869425,"threshold_uncertainty_score":0.9998742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08381462230372427,"score_gpt":0.3667691809351271,"score_spread":0.2829545586314028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}