{"id":"W2784453912","doi":"10.3390/v10010012","title":"Sustained IFN-I Expression during Established Persistent Viral Infection: A “Bad Seed” for Protective Immunity","year":2017,"lang":"en","type":"review","venue":"Viruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Lymphocytic choriomeningitis; Immunology; Biology; Immune system; Immunity; Virology; Simian immunodeficiency virus; Innate immune system; Virus; Chronic infection; clone (Java method); Viral pathogenesis; Viral replication; CD8; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003296046,0.0004549597,0.0006864946,0.0009407206,0.0002046516,0.0008313856,0.0004759428,0.0007891899,0.002274191],"category_scores_gemma":[0.0004057617,0.0001567913,0.0002405202,0.0009093722,0.000339443,0.001052835,0.0004483684,0.00145339,0.001484048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004165759,"about_ca_system_score_gemma":0.0007938486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004225796,"about_ca_topic_score_gemma":0.0008005892,"domain_scores_codex":[0.9998982,0.00001604116,0.00001625574,0.00001934428,0.00003708538,0.00001311332],"domain_scores_gemma":[0.9998586,0.00005468082,0.00002109738,0.000005455433,0.0000426422,0.00001745389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008744683,0.00004852851,0.0002216697,0.01120871,0.00004498205,0.000204666,0.00008864883,0.0002517185,0.005582506,0.005725556,0.02789813,0.9486374],"study_design_scores_gemma":[0.000008149107,0.00006248469,0.000697376,0.001987118,0.00003714044,0.001051378,0.00007630738,0.00005789994,0.001015138,0.002188703,0.9928064,0.00001182019],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000282683,0.9973382,0.0001935582,0.0004823442,0.0003542266,0.000003458764,0.00002059722,0.000009967023,0.001314957],"genre_scores_gemma":[0.001184255,0.9972476,0.0001967728,0.0002511129,0.0002192151,0.000005432423,0.00003124618,0.000002194399,0.0008620985],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002274191,"threshold_uncertainty_score":0.007607937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08381462230372427,"score_gpt":0.3667691809351271,"score_spread":0.2829545586314028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}