{"id":"W2784493877","doi":"10.1016/j.celrep.2017.12.103","title":"ICAMs Are Not Obligatory for Functional Immune Synapses between Naive CD4 T Cells and Lymph Node DCs","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Research Council; Azrieli Foundation; Israel Science Foundation; Rising Tide Foundation; Tides Foundation; Minerva Foundation; Abu Dhabi Education Council; Flight Attendant Medical Research Institute","keywords":"Priming (agriculture); Cell biology; T cell; Immune system; Antigen-presenting cell; Immunological synapse; CD40; Naive T cell; Biology; Dendritic cell; Immunology; Cytotoxic T cell; Lymph node; T-cell receptor; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105614,0.000170209,0.0001538338,0.0001087491,0.000143738,0.0004221063,0.0002021275,0.0002989635,0.001265737],"category_scores_gemma":[0.0002025315,0.0001616247,0.0001303658,0.00008086956,0.0002480635,0.0003574341,0.0002356473,0.0006512937,0.0002678521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002823179,"about_ca_system_score_gemma":0.0001947815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003205051,"about_ca_topic_score_gemma":0.000506215,"domain_scores_codex":[0.9998155,0.00002008041,0.00001155797,0.00004159079,0.00004325967,0.0000679828],"domain_scores_gemma":[0.9998294,0.00003770264,0.00004165218,0.00003085625,0.00001831299,0.00004208272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003371802,0.000006953869,0.00025383,0.00001329908,0.000001676226,0.00003186652,0.000008464226,0.00001551154,0.9989323,0.0001658115,0.00001260256,0.000524092],"study_design_scores_gemma":[0.0000197561,0.0001335479,0.01162248,0.00001001775,0.0000258326,0.0005700934,0.00005257592,0.0006872175,0.983682,0.0002426562,0.002950138,0.000003848942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968172,0.0005196085,0.001504438,0.00004515644,0.00001434592,0.000006521553,0.00007986432,0.00003054523,0.0009820907],"genre_scores_gemma":[0.9977391,0.0001846132,0.001085079,0.00002513172,0.00000620792,0.00001051088,0.0001371658,0.00001028259,0.000802004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001265737,"threshold_uncertainty_score":0.004234314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01619281853561427,"score_gpt":0.2300637006764146,"score_spread":0.2138708821408004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}