{"id":"W2785568898","doi":"10.1371/journal.pgen.1007204","title":"An alternatively spliced form affecting the Marked Box domain of Drosophila E2F1 is required for proper cell cycle regulation","year":2018,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute","keywords":"Biology; E2F; Imaginal disc; Drosophila melanogaster; Repressor; Genetics; Cell biology; Cell cycle; Cell Cycle Protein; Transcription factor; Mitosis; Regulator; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009318814,0.0004814191,0.0002452785,0.0002572467,0.0002697318,0.0002011075,0.0002217849,0.0003626174,0.004542368],"category_scores_gemma":[0.0001245886,0.0001349251,0.0003014096,0.0001691881,0.0001882636,0.0001563421,0.0002502944,0.0006068366,0.002808629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003117928,"about_ca_system_score_gemma":0.0001871746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006302816,"about_ca_topic_score_gemma":0.001095084,"domain_scores_codex":[0.9998971,0.000009317731,0.0000104255,0.00003579742,0.00003256935,0.00001489748],"domain_scores_gemma":[0.9998916,0.00001339705,0.000032688,0.00001444804,0.000009651872,0.0000382273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005477978,0.00001394239,0.0002530464,0.00002619549,0.000004694175,0.0001351614,0.000006426159,0.0000359609,0.9973369,0.0001434543,0.00009636586,0.001893096],"study_design_scores_gemma":[0.00003268664,0.0001004623,0.01345383,0.00001282373,0.0000199923,0.001360338,0.00002720281,0.0009583537,0.9597012,0.0001445005,0.02417643,0.00001216586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9707565,0.003675055,0.01684626,0.000208134,0.0001982482,0.00005863738,0.002843172,0.0003985319,0.005015521],"genre_scores_gemma":[0.9823709,0.0005547503,0.004119048,0.0001080921,0.00001732133,0.00004251359,0.003011752,0.0001052996,0.009670353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004542368,"threshold_uncertainty_score":0.01519579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02399490960340007,"score_gpt":0.2770936777408813,"score_spread":0.2530987681374813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}