{"id":"W2785766139","doi":"10.1101/gad.301887.117","title":"Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors","year":2018,"lang":"en","type":"article","venue":"Genes & Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Science and Technology Agency; Eisai; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Keio University; Research Center Network for Realization of Regenerative Medicine; Eisai Canada; Japan Agency for Medical Research and Development","keywords":"Biology; Chromatin; Cell biology; Neural stem cell; Progenitor cell; Polycomb-group proteins; Stem cell; Genetics; Transcription factor; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003719776,0.0001582818,0.0001366188,0.00004282381,0.0002469577,0.00003149411,0.0004878795,0.00009403617,0.00003524582],"category_scores_gemma":[0.000004623357,0.0001171011,0.00006517451,0.0001268695,0.0001756813,0.00000701225,0.0004135516,0.00005999105,0.00004357046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000028507,"about_ca_system_score_gemma":0.0001405009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001998178,"about_ca_topic_score_gemma":0.00007951023,"domain_scores_codex":[0.9985732,0.00008947671,0.0003271286,0.000324943,0.0003606326,0.0003246316],"domain_scores_gemma":[0.9991767,0.000006084549,0.0001199399,0.0004336495,0.0001963602,0.00006730044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001981737,0.0000466169,0.00263027,0.00004850019,0.00004550368,0.000001365745,0.0002179489,0.00001326534,0.9891218,0.000009436662,0.0009228754,0.006922619],"study_design_scores_gemma":[0.0002061856,0.0001154236,0.01194173,0.0000114133,0.000007987241,0.000006576062,0.00009464839,0.00007577692,0.9774587,0.00001903404,0.009915924,0.0001466463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975469,0.001070199,0.000131149,0.0000582972,0.0001468502,0.0003333769,0.000003288633,0.00001206526,0.0006978962],"genre_scores_gemma":[0.995311,0.00005695521,0.000928322,0.00003720714,0.0001898148,0.0000349617,0.0000391716,0.00002256774,0.00337999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01166313,"threshold_uncertainty_score":0.4775245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01985595574860994,"score_gpt":0.2734004964448463,"score_spread":0.2535445406962363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}