{"id":"W2785907460","doi":"10.1182/blood.v130.suppl_1.5211.5211","title":"Clinical Pharmacology of CTL019 in Patients with Relapsed/Refractory (r/r) Diffuse Large B-Cell Lymphoma (DLBCL)","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Hospital","funders":"","keywords":"Oncology; Biology; Internal medicine; Proportional hazards model; Diffuse large B-cell lymphoma; Medicine; Pharmacology; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005669411,0.0002183378,0.0005243439,0.0001616587,0.0001657688,0.0003716675,0.0002198146,0.0002124285,0.0007769405],"category_scores_gemma":[0.0007889937,0.0001086818,0.0002495756,0.0001912961,0.0001635951,0.0002307365,0.0001415847,0.0007166495,0.0002962151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005409917,"about_ca_system_score_gemma":0.0004816628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003342349,"about_ca_topic_score_gemma":0.001139554,"domain_scores_codex":[0.99975,0.0001103365,0.00002380087,0.0000395742,0.00004850744,0.00002779535],"domain_scores_gemma":[0.9995399,0.0001210262,0.0001836516,0.00002490465,0.00005075895,0.0000798417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.08704106,0.007223176,0.2896895,0.001115113,0.0008701586,0.001612506,0.0006412517,0.003966989,0.1623521,0.000299482,0.005459343,0.4397295],"study_design_scores_gemma":[0.01884373,0.2542438,0.6377328,0.0001955469,0.00108517,0.007969477,0.0004833938,0.007506434,0.04515132,0.0005162623,0.0262002,0.0000718829],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940394,0.003570467,0.0005187568,0.0002060518,0.00001492465,0.0001405857,0.0002899875,0.00005857861,0.001161287],"genre_scores_gemma":[0.9975252,0.0008691142,0.0005646186,0.0002301911,0.00002031165,0.00007944593,0.0003390521,0.000007548705,0.00036463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007769405,"threshold_uncertainty_score":0.003925145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.024839222204071,"score_gpt":0.3442835509791612,"score_spread":0.3194443287750902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}