{"id":"W2786076295","doi":"10.1038/nrrheum.2018.17","title":"Proteinases and their receptors in inflammatory arthritis: an overview","year":2018,"lang":"en","type":"review","venue":"Nature Reviews Rheumatology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; University of Toronto; Mount Sinai Hospital; Toronto Western Hospital; University Health Network","funders":"Health Canada; Krembil Foundation; University Health Network","keywords":"Receptor; Arthritis; Inflammation; Medicine; Rheumatoid arthritis; Osteoarthritis; Immunology; Proteolytic enzymes; Inflammatory arthritis; Signal transduction; Cell biology; Biology; Enzyme; Pathology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001224293,0.0008045677,0.005987453,0.0005043783,0.00007458308,0.00003488929,0.0002634699,0.002242303,0.0003274612],"category_scores_gemma":[0.0004717512,0.0005389295,0.000526735,0.0005420813,0.0001855132,0.0001378039,0.0001308264,0.001773811,0.000201815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008683252,"about_ca_system_score_gemma":0.0003542528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008141468,"about_ca_topic_score_gemma":0.00009390101,"domain_scores_codex":[0.9954569,0.001262444,0.001734521,0.0009184936,0.0001736691,0.0004539821],"domain_scores_gemma":[0.9976875,0.0001572259,0.0008595562,0.0009284426,0.0001004664,0.0002667932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007020081,0.0001005502,0.00004256277,0.04850456,0.00008491163,0.00001658423,0.00005480758,1.053144e-9,3.44913e-7,0.004665061,0.0008944171,0.9456292],"study_design_scores_gemma":[0.0004699871,0.0002022044,0.00001113241,0.1285927,0.0002044592,0.001687469,0.00001319433,0.000001691853,0.000003259843,0.0003296429,0.8680971,0.0003872057],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006099693,0.9946779,0.000006194151,0.00007706435,0.0006829555,0.004243938,0.0000121639,0.00009828151,0.0001404756],"genre_scores_gemma":[0.00002521712,0.9980487,0.0004312105,0.0003208721,0.0001082261,0.0006955549,0.0002180853,0.00009973096,0.00005240982],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.945242,"threshold_uncertainty_score":0.9997062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06886460363360052,"score_gpt":0.369507535054415,"score_spread":0.3006429314208144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}