{"id":"W2786602688","doi":"10.1021/acsomega.7b01779","title":"Selective Photoinduced Antibacterial Activity of Amoxicillin-Coated Gold Nanoparticles: From One-Step Synthesis to in Vivo Cytocompatibility","year":2018,"lang":"en","type":"article","venue":"ACS Omega","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Fondo para la Investigación Científica y Tecnológica; Canada Research Chairs; Division of Materials Research; Consejo Nacional de Investigaciones Científicas y Técnicas; Natural Sciences and Engineering Research Council of Canada; University of Ottawa","keywords":"In vivo; Biodistribution; Biocompatibility; Chemistry; Amoxicillin; Antibiotics; Bacteria; Staphylococcus aureus; Antibacterial activity; Antibacterial agent; Fluorescence microscope; Colloidal gold; Nanoparticle; In vitro; Combinatorial chemistry; Nuclear chemistry; Nanotechnology; Materials science; Fluorescence; Biochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000202646,0.0002544869,0.0005178388,0.0001590659,0.00003379964,0.000027306,0.0002781908,0.000164006,0.00005327457],"category_scores_gemma":[0.0002495368,0.0002689499,0.00006343583,0.0007110948,0.00008452556,0.0002830958,0.00006418698,0.0001701695,0.00004891999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003499377,"about_ca_system_score_gemma":0.00005008321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001497561,"about_ca_topic_score_gemma":0.002474106,"domain_scores_codex":[0.9985142,0.00004512189,0.0004207395,0.0003476833,0.0002436539,0.0004285792],"domain_scores_gemma":[0.9988362,0.0003341407,0.00008255622,0.0005073526,0.0001202448,0.0001195529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004391994,0.0001403357,0.003048278,0.00003609257,0.00009425313,0.000001827605,0.0008106297,0.0001175929,0.9935562,0.000004165628,0.0001089028,0.001642539],"study_design_scores_gemma":[0.000567073,0.0001676735,0.02333714,0.0001335394,0.00002908375,3.119881e-7,0.00003673903,0.001183744,0.9740423,0.00008012415,0.0001359537,0.000286346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977757,0.00001195262,0.0002895193,0.00001075386,0.0003998658,0.0006799153,0.0002801043,0.0001747602,0.0003774588],"genre_scores_gemma":[0.998979,0.000007366887,0.0007070891,0.00002419521,0.0001488669,0.00006562343,0.000003171874,0.00005579263,0.000008885901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02028887,"threshold_uncertainty_score":0.9999763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01833813026486673,"score_gpt":0.2361907814932889,"score_spread":0.2178526512284222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}