{"id":"W2786639886","doi":"10.1016/j.cmi.2018.01.030","title":"ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Immune checkpoint inhibitors, cell adhesion inhibitors, sphingosine-1-phosphate receptor modulators and proteasome inhibitors)","year":2018,"lang":"en","type":"review","venue":"Clinical Microbiology and Infection","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"Sphingosine-1-phosphate; Immune system; Perspective (graphical); Immunology; Medicine; Biology; Sphingosine; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002610991,0.000657487,0.001814554,0.001450087,0.0002435443,0.0008952453,0.0009571504,0.001392627,0.004111811],"category_scores_gemma":[0.002535533,0.0001894098,0.001411069,0.001053812,0.0003168085,0.000791076,0.0008223488,0.00204367,0.001276021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007290884,"about_ca_system_score_gemma":0.002874198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001262931,"about_ca_topic_score_gemma":0.002445421,"domain_scores_codex":[0.999332,0.0001746761,0.0001584125,0.00005059491,0.0002283975,0.00005590399],"domain_scores_gemma":[0.9987582,0.0006113789,0.0002379385,0.00002849124,0.0002855523,0.0000785001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003551056,0.00005680237,0.0002342545,0.02661862,0.0003661271,0.00008552236,0.00003480024,0.0001401046,0.0005562651,0.002728353,0.06695576,0.9018683],"study_design_scores_gemma":[0.0002462165,0.0001771521,0.001039854,0.02371074,0.0008565818,0.000446203,0.00003693042,0.00003971748,0.0004398017,0.0009860146,0.9720023,0.00001847708],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001107125,0.9964702,0.0001405819,0.001047008,0.0006685107,0.00002883831,0.0001296745,0.000008537387,0.001395899],"genre_scores_gemma":[0.001178031,0.9949329,0.0005692479,0.001610015,0.0004311185,0.00005929191,0.000214852,0.000004200516,0.001000262],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004111811,"threshold_uncertainty_score":0.01380843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03306650589934367,"score_gpt":0.3372703608189124,"score_spread":0.3042038549195687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}