{"id":"W2786774422","doi":"10.1139/cjpp-2017-0630","title":"Oral hormonal therapy with ethinylestradiol–levonorgestrel improves insulin resistance, obesity, and glycogen synthase kinase-3 independent of circulating mineralocorticoid in estrogen-deficient rats","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Endocrinology; Internal medicine; Ethinylestradiol; Estrogen; Levonorgestrel; Insulin resistance; Mineralocorticoid; Insulin; Medicine; Aldosterone; Biology; Population","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001765137,0.0007023022,0.0007438301,0.0008227513,0.0002383837,0.0002643507,0.0003230932,0.0003608251,0.001288463],"category_scores_gemma":[0.0001716841,0.0002766199,0.0004615143,0.0002696853,0.0004255627,0.0003418882,0.0002080475,0.0009410814,0.0002851966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002332553,"about_ca_system_score_gemma":0.0004780325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001113807,"about_ca_topic_score_gemma":0.002425077,"domain_scores_codex":[0.9998624,0.00001768837,0.00002025729,0.00002813477,0.00002878148,0.00004271921],"domain_scores_gemma":[0.9997295,0.00001967548,0.00008558708,0.00002820528,0.00002492927,0.0001122178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01022823,0.001987092,0.001378724,0.0001774566,0.00006353246,0.0001529589,0.00006787582,0.0001575019,0.9754257,0.00009604348,0.0001814259,0.01008352],"study_design_scores_gemma":[0.001881914,0.02768751,0.03555282,0.00006110554,0.0002999408,0.000366332,0.0004166114,0.001551978,0.9268581,0.0002672857,0.005002898,0.00005353755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964109,0.001718754,0.000656557,0.0001664473,0.00005685884,0.00002734992,0.0003189834,0.0001196718,0.0005244],"genre_scores_gemma":[0.9893484,0.002673038,0.001724264,0.0001656843,0.00005752882,0.0001007571,0.0007768968,0.00002961578,0.005123731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001288463,"threshold_uncertainty_score":0.004310369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008490070731309028,"score_gpt":0.2421797846237906,"score_spread":0.2336897138924816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}