{"id":"W2786854070","doi":"10.1016/j.stem.2018.01.011","title":"Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies","year":2018,"lang":"en","type":"review","venue":"Cell stem cell","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":450,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"National Cancer Institute; Damon Runyon Cancer Research Foundation","keywords":"Biology; Haematopoiesis; Somatic evolution in cancer; Immunology; Cancer research; Evolutionary biology; Genetics; Stem cell; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006928081,0.0006240345,0.0008797093,0.002247104,0.0002382253,0.001335946,0.0006916331,0.001224843,0.004622863],"category_scores_gemma":[0.002190788,0.0002279061,0.0003486684,0.001962303,0.0008299509,0.001552646,0.00107432,0.001758211,0.001354004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000700838,"about_ca_system_score_gemma":0.001890307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008523156,"about_ca_topic_score_gemma":0.001727198,"domain_scores_codex":[0.999774,0.00004455575,0.00003956972,0.00004511907,0.00007177775,0.00002499601],"domain_scores_gemma":[0.9992703,0.0004297039,0.00009825308,0.00002079818,0.000129793,0.00005115301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000717763,0.00002790988,0.0004648583,0.01305051,0.00007936938,0.0002739073,0.00007372317,0.000258935,0.000522427,0.006986917,0.05904856,0.9191412],"study_design_scores_gemma":[0.00001750337,0.0000347557,0.0006784776,0.004674732,0.0001326512,0.001478217,0.00007453243,0.00005891077,0.0001934462,0.002930202,0.9897137,0.00001285565],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008744441,0.9976149,0.0001034506,0.0006559685,0.0004847751,0.000002883631,0.00001972695,0.000006047669,0.001024828],"genre_scores_gemma":[0.000896732,0.9968719,0.0001479328,0.0006069407,0.0008063046,0.000004387172,0.00003374997,0.000001841928,0.0006302382],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004622863,"threshold_uncertainty_score":0.01546508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03664998042485567,"score_gpt":0.3074273032066217,"score_spread":0.270777322781766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}