{"id":"W2786900457","doi":"10.1371/journal.pone.0192659","title":"KSHV oral shedding and plasma viremia result in significant changes in the extracellular tumorigenic miRNA expression profile in individuals infected with the malaria parasite","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Uganda Cancer Institute; Children’s Hospital of Wisconsin Research Institute; Seattle Children's Research Institute; National Institute of Dental and Craniofacial Research; Fred Hutchinson Cancer Research Center","keywords":"Biology; microRNA; Microvesicles; Virology; Kaposi's sarcoma-associated herpesvirus; Viremia; Malaria; Immunology; Small RNA; Virus; Viral disease; Genetics; Gene; Herpesviridae","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007482389,0.0001436331,0.0002061746,0.0002798183,0.0002354582,0.000335098,0.00005446043,0.0001669352,0.001161483],"category_scores_gemma":[0.0003614032,0.0002009208,0.0001115132,0.0001997825,0.0001465006,0.0001368795,0.0002409427,0.0002212307,0.0001844814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007636222,"about_ca_system_score_gemma":0.00006916416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004237941,"about_ca_topic_score_gemma":0.0004380644,"domain_scores_codex":[0.9999185,0.00001476016,0.000007659298,0.00002684522,0.00001394142,0.00001836736],"domain_scores_gemma":[0.9998926,0.00001687975,0.00005035961,0.000007728217,0.00001359592,0.00001886966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002791243,0.0001431034,0.5389284,0.0002487902,0.0001026473,0.001592817,0.002251338,0.0001290559,0.4298365,0.0001353233,0.0003311439,0.02350964],"study_design_scores_gemma":[0.000009104844,0.0005193843,0.9756832,0.00001954901,0.0000411012,0.002879109,0.0009196405,0.0003365829,0.01849307,0.00008673635,0.00100177,0.00001076697],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995131,0.0001861078,0.00006985142,0.000006342457,0.000001382565,0.00000279661,0.00009075586,0.000003133304,0.0001263986],"genre_scores_gemma":[0.9992114,0.000112242,0.0001901675,0.00001229001,0.000001969393,0.000007089879,0.0001065704,0.000002187452,0.0003560892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001161483,"threshold_uncertainty_score":0.003885567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02009719716821714,"score_gpt":0.2396699977790385,"score_spread":0.2195728006108214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}