{"id":"W2786912169","doi":"10.1016/j.celrep.2018.01.020","title":"Learning and Age-Related Changes in Genome-wide H2A.Z Binding in the Mouse Hippocampus","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of General Medical Sciences; National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Connaught Fund; Hospital for Sick Children","keywords":"Histone; Neuroplasticity; Hippocampus; Biology; Transcription (linguistics); Nucleosome; Gene; Gene expression; Basal (medicine); Neuroscience; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006000844,0.0000869286,0.00008754053,0.00006710178,0.00005805929,0.00002452251,0.00004799635,0.0001147897,0.00001048635],"category_scores_gemma":[0.0001246231,0.00007197518,0.00001802509,0.0001070209,0.00006418601,0.000001845761,0.00005287844,0.0001083642,0.000002277354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009756344,"about_ca_system_score_gemma":0.00001700677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002686482,"about_ca_topic_score_gemma":0.0003046734,"domain_scores_codex":[0.9992281,0.00008124868,0.0001955402,0.0002522555,0.00007522012,0.0001677019],"domain_scores_gemma":[0.999648,0.00001765048,0.0001115212,0.0001710193,0.00002281121,0.00002900515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006131219,0.00002274744,0.1526382,0.00000907788,0.000003783502,0.0001254297,0.0006651129,0.00004555844,0.8443657,0.00000111021,0.00001551587,0.002101707],"study_design_scores_gemma":[0.0004231248,0.000464658,0.09571011,0.00001943605,0.00001230869,0.00003915757,0.0005466965,0.00006467767,0.8608419,0.0005966676,0.04099389,0.0002873391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946254,0.001522795,0.0000228198,0.00006441316,0.00006620589,0.0001361396,3.099821e-7,0.000005154664,0.003556693],"genre_scores_gemma":[0.9978723,0.0006857889,0.00008167764,0.00004705729,0.00006659925,0.000009205548,0.00006022696,0.00001300394,0.001164154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05692804,"threshold_uncertainty_score":0.2935063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009250712258138415,"score_gpt":0.2393575829803978,"score_spread":0.2301068707222594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}