{"id":"W2787440058","doi":"10.1172/jci.insight.94040","title":"Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction","year":2018,"lang":"en","type":"article","venue":"JCI Insight","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":172,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Cancer Institute NSW; Wellcome Trust; National Health and Medical Research Council; McMaster University; Johns Hopkins University","keywords":"Medicine; Hypoxia (environmental); Ileum; COPD; Pathology; Inflammation; Gastrointestinal tract; Pathogenesis; Internal medicine; Immunology; Gastroenterology; Chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002271319,0.0003621499,0.0004580902,0.0003447898,0.0002698828,0.00007363842,0.0002780535,0.0002342602,0.001550307],"category_scores_gemma":[0.000199657,0.0003026661,0.0001747561,0.0005056909,0.0005820831,0.0003631711,0.000199243,0.0006207445,0.0004419752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00118813,"about_ca_system_score_gemma":0.0007804362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007563622,"about_ca_topic_score_gemma":0.00004437464,"domain_scores_codex":[0.997172,0.0001498763,0.0003956601,0.0007283332,0.0008942531,0.0006598774],"domain_scores_gemma":[0.9980935,0.0001171883,0.0001674053,0.000792313,0.0004311873,0.00039845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001753006,0.001005066,0.5449065,0.004174334,0.001151264,0.001832832,0.003578552,0.00001123354,0.2594041,0.002013853,0.01564747,0.1645218],"study_design_scores_gemma":[0.003260839,0.001685568,0.9399751,0.001595385,0.0002664652,0.001104105,0.0007796812,0.0004788794,0.02907634,0.0002196395,0.02102423,0.000533766],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743581,0.005797029,0.000102602,0.0007921663,0.001055156,0.0008100722,0.00001674693,0.000247624,0.01682052],"genre_scores_gemma":[0.9930564,0.0001184949,0.000073919,0.00022428,0.003375163,0.0001018823,0.00007436319,0.00007322191,0.002902299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3950686,"threshold_uncertainty_score":0.9999425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03398049595070712,"score_gpt":0.2846056528968059,"score_spread":0.2506251569460988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}