{"id":"W2787725515","doi":"10.1016/s1470-2045(18)30079-2","title":"Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial","year":2018,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":623,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Hôpital Notre-Dame; Université de Sherbrooke","funders":"Agenzia Italiana del Farmaco, Ministero della Salute; National Health and Medical Research Council; Cancer Research UK; Cancer Australia; Strong; Cancer Research Institute","keywords":"Medicine; Endometrial cancer; Radiation therapy; Chemoradiotherapy; Carboplatin; Internal medicine; Oncology; Lymphadenectomy; Clinical endpoint; Clinical trial; Surgery; Gynecology; Cancer; Chemotherapy; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004249917,0.001120071,0.001538036,0.0002693076,0.0003112155,0.0009205512,0.0006866826,0.001223446,0.005689833],"category_scores_gemma":[0.004318621,0.0003276549,0.002723313,0.0003971079,0.0006775373,0.0007874689,0.0005037318,0.00247681,0.0006202928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005928554,"about_ca_system_score_gemma":0.001122316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005404243,"about_ca_topic_score_gemma":0.001572935,"domain_scores_codex":[0.9987232,0.0009687902,0.00005636508,0.00009625733,0.00006581242,0.00008956663],"domain_scores_gemma":[0.9983669,0.0006539075,0.000423925,0.0001468659,0.00009558004,0.0003128625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9695164,0.00336584,0.0009940005,0.001009446,0.001675523,0.00004753696,0.00005730536,0.0004689421,0.001073977,0.0001309508,0.001637125,0.02002303],"study_design_scores_gemma":[0.9456088,0.04862444,0.002495395,0.00010713,0.001002071,0.00006812925,0.00002309823,0.0003312633,0.0002529706,0.000248109,0.001223139,0.00001555415],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9646283,0.0146822,0.001678219,0.002016924,0.000794551,0.009069654,0.003454865,0.0001540503,0.003521291],"genre_scores_gemma":[0.9641572,0.006366942,0.005344941,0.002684894,0.0006662664,0.01277046,0.003876712,0.00005192068,0.004080635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005689833,"threshold_uncertainty_score":0.02247596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1177522718809392,"score_gpt":0.4363642117302591,"score_spread":0.3186119398493199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}