{"id":"W2787725515","doi":"10.1016/s1470-2045(18)30079-2","title":"Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial","year":2018,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":623,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Hôpital Notre-Dame; Université de Sherbrooke","funders":"Agenzia Italiana del Farmaco, Ministero della Salute; National Health and Medical Research Council; Cancer Research UK; Cancer Australia; Strong; Cancer Research Institute","keywords":"Medicine; Endometrial cancer; Radiation therapy; Chemoradiotherapy; Carboplatin; Internal medicine; Oncology; Lymphadenectomy; Clinical endpoint; Clinical trial; Surgery; Gynecology; Cancer; Chemotherapy; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001520585,0.0002744739,0.001702842,0.0001646222,0.0001380012,0.00003524904,0.0006694446,0.000154892,0.0007030406],"category_scores_gemma":[0.0006713935,0.000158844,0.00007974094,0.0004761177,0.0003628282,0.000154516,0.00005161526,0.0002224708,0.000004294282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007291508,"about_ca_system_score_gemma":0.0004974554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001387832,"about_ca_topic_score_gemma":0.000602723,"domain_scores_codex":[0.9976215,0.0003122629,0.0006689929,0.0004944084,0.000380395,0.0005224056],"domain_scores_gemma":[0.9966971,0.0014475,0.0007284566,0.0005978317,0.0003248928,0.0002041909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8196641,0.003265435,0.0000633989,0.0000186042,0.001719213,0.00002099078,0.0006689716,0.000005692373,0.00228332,0.00003377638,0.0009643532,0.1712921],"study_design_scores_gemma":[0.8416431,0.07548951,0.0002754802,0.0000296774,0.0003906892,0.00001223429,0.0000911441,0.0002507189,0.00489986,0.00006868037,0.0766901,0.0001588018],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865357,0.0005120862,0.0001900373,0.002888851,0.002946197,0.004889138,0.0008319986,0.00004585501,0.001160155],"genre_scores_gemma":[0.9662182,0.004883563,0.01096359,0.00131773,0.01333191,0.002169529,0.0002140097,0.00007160329,0.0008298186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1711333,"threshold_uncertainty_score":0.7697802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1177522718809392,"score_gpt":0.4363642117302591,"score_spread":0.3186119398493199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}