{"id":"W2787902098","doi":"10.1038/nature25973","title":"Environment dominates over host genetics in shaping human gut microbiota","year":2018,"lang":"en","type":"article","venue":"Nature","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2975,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Abisch-Frenkel-Stiftung; Israel Science Foundation; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust; Rijksuniversiteit Groningen; Stiftelsen Kristian Gerhard Jebsen; Canadian Institute for Advanced Research; Leona M. and Harry B. Helmsley Charitable Trust; Bill and Melinda Gates Foundation; Howard Hughes Medical Institute","keywords":"Microbiome; Biology; Metagenomics; Human microbiome; Microbial genetics; Host (biology); Human genetics; Genetics; Evolutionary biology; Human Microbiome Project; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008961828,0.000249306,0.0004408495,0.000377499,0.0003118086,0.001477894,0.0001942039,0.000661437,0.002137246],"category_scores_gemma":[0.0009940435,0.0002129198,0.0001824893,0.0003121456,0.0008286724,0.000651003,0.0006802009,0.0005079083,0.0003171736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003019083,"about_ca_system_score_gemma":0.0004868216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009193854,"about_ca_topic_score_gemma":0.002926623,"domain_scores_codex":[0.9993706,0.0002333897,0.0000268386,0.0001172036,0.0001496393,0.0001023042],"domain_scores_gemma":[0.9995136,0.0001610132,0.00009670272,0.0000504968,0.00004699266,0.0001311707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00197434,0.000212314,0.5585849,0.0005385022,0.0008390603,0.001557991,0.001030475,0.002249906,0.2193801,0.03136963,0.003101095,0.1791618],"study_design_scores_gemma":[0.00005131003,0.0005583109,0.9143332,0.000276867,0.0005618147,0.001891524,0.001593331,0.002628793,0.02184103,0.02895007,0.02723468,0.00007910199],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9442769,0.02971218,0.006535346,0.003981133,0.0003747688,0.00001431575,0.0003418234,0.00008617841,0.01467738],"genre_scores_gemma":[0.9923029,0.004325974,0.001083253,0.0006356706,0.0001546539,0.000004572814,0.00003941495,0.00003488243,0.001418678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002137246,"threshold_uncertainty_score":0.007149816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008092283795822382,"score_gpt":0.278266901828381,"score_spread":0.2701746180325587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}