{"id":"W2787915872","doi":"10.7759/cureus.2238","title":"Abscopal Effect in a Stage IV Melanoma Patient who Progressed on Pembrolizumab","year":2018,"lang":"en","type":"article","venue":"Cureus","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Abscopal effect; Pembrolizumab; Radiation therapy; Melanoma; Lesion; Mucosal melanoma; Lung; Larynx; Radiology; Stage (stratigraphy); Immunotherapy; Surgery; Internal medicine; Cancer; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001525379,0.0005073652,0.0005209265,0.0006078015,0.001092007,0.0005958166,0.0002604689,0.001334686,0.001074472],"category_scores_gemma":[0.0007898724,0.0003112113,0.0003696721,0.0003532025,0.0003905322,0.0005086384,0.0004083354,0.001249095,0.0004452067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003292688,"about_ca_system_score_gemma":0.0002896492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001008742,"about_ca_topic_score_gemma":0.002137578,"domain_scores_codex":[0.9998641,0.00001942073,0.00001065005,0.00002648936,0.00001866771,0.00006069248],"domain_scores_gemma":[0.9997658,0.00004923058,0.00004052924,0.00002011048,0.00001816413,0.0001062557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00008895893,0.00005542899,0.01170314,0.00003475817,0.000007455347,0.9814888,0.0001869172,0.00006818065,0.001885063,0.0001271323,0.0002842668,0.004069946],"study_design_scores_gemma":[0.00001318097,0.0002109824,0.007623566,0.00001574967,0.00002290361,0.9890434,0.000116941,0.0003669943,0.0008316019,0.000140897,0.001606215,0.000007657576],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850923,0.003710259,0.001137903,0.001091178,0.000136754,0.00008245633,0.00008765134,0.00007916041,0.008582345],"genre_scores_gemma":[0.9961258,0.001334288,0.0004553416,0.0004188789,0.0001541615,0.00001055289,0.00005193067,0.00001118424,0.001437953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001334686,"threshold_uncertainty_score":0.003594458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01182194189274016,"score_gpt":0.2919495731585549,"score_spread":0.2801276312658147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}