{"id":"W2787915872","doi":"10.7759/cureus.2238","title":"Abscopal Effect in a Stage IV Melanoma Patient who Progressed on Pembrolizumab","year":2018,"lang":"en","type":"article","venue":"Cureus","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Abscopal effect; Pembrolizumab; Radiation therapy; Melanoma; Lesion; Mucosal melanoma; Lung; Larynx; Radiology; Stage (stratigraphy); Immunotherapy; Surgery; Internal medicine; Cancer; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001394222,0.0001465822,0.0002351672,0.00007286356,0.00004133042,0.00001548994,0.0000759724,0.00008436224,0.0005486705],"category_scores_gemma":[0.00003656324,0.0001080169,0.00007457925,0.0001644483,0.0001055329,0.00003807041,0.0000203278,0.0001212157,0.00008097123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001835448,"about_ca_system_score_gemma":0.00007020021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000195011,"about_ca_topic_score_gemma":0.0001792157,"domain_scores_codex":[0.9990579,0.00005387621,0.0001906112,0.0002311788,0.0002124862,0.0002538905],"domain_scores_gemma":[0.9994863,0.0000398193,0.00005897485,0.0003122794,0.00003486093,0.00006778667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1224493,0.0026107,0.2575783,0.0008067779,0.0008070084,0.001138493,0.01025403,0.000002430782,0.08818324,0.0005011386,0.0362131,0.4794555],"study_design_scores_gemma":[0.0319634,0.05153021,0.5530017,0.001734063,0.0001003904,0.00006647584,0.0002545091,0.0004011992,0.1764839,0.00006013966,0.1837013,0.0007027257],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860994,0.0009044398,0.000002989629,0.0002728499,0.0003205598,0.0006626612,0.000009122368,0.00004804533,0.01167998],"genre_scores_gemma":[0.9982998,0.00004113745,0.00003965365,0.0006244223,0.0002038808,0.00006580583,0.00001044308,0.00002149081,0.0006933848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4787528,"threshold_uncertainty_score":0.6007557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01182194189274016,"score_gpt":0.2919495731585549,"score_spread":0.2801276312658147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}