{"id":"W2787966870","doi":"10.1101/254201","title":"Exposure to the oral host niche yields rapid phenotypic and genotypic diversification in <i>Candida albicans</i>","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Candida albicans; Ploidy; Phenotype; Genotype; Aneuploidy; Loss of heterozygosity; Genetics; Corpus albicans; Host adaptation; Genome; Allele; Chromosome; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001325005,0.0002263223,0.0002030011,0.0001962906,0.0001698096,0.0004820888,0.0001566528,0.0002229939,0.001202074],"category_scores_gemma":[0.0001623771,0.0001164818,0.0001875297,0.0001282028,0.0001268336,0.0001095845,0.0003019103,0.0005216142,0.0002152521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000153407,"about_ca_system_score_gemma":0.0001143969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000732257,"about_ca_topic_score_gemma":0.0007683772,"domain_scores_codex":[0.9998136,0.00002595247,0.00001746685,0.00004385751,0.00005209043,0.0000469607],"domain_scores_gemma":[0.9998585,0.00002473525,0.00003667401,0.00002457494,0.00002309058,0.00003234014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004403832,0.00001280525,0.0006591536,0.000009504502,0.000002640931,0.00003182345,0.000008768173,0.00001735066,0.9984939,0.000009866072,0.00001898475,0.000691131],"study_design_scores_gemma":[0.000007246274,0.0006496097,0.09121546,0.00001281608,0.00002300657,0.0006902755,0.0001295072,0.0006692932,0.9052037,0.00004412754,0.001344399,0.00001057842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983577,0.0002119433,0.0006067001,0.00002402953,0.000004353927,0.00001204382,0.0002113749,0.00002445927,0.0005473219],"genre_scores_gemma":[0.9973238,0.0001671222,0.0008967699,0.0000651158,0.00000640879,0.00001948844,0.0005239362,0.00002081545,0.0009766094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001202074,"threshold_uncertainty_score":0.004021347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01803777408636093,"score_gpt":0.2363207445944578,"score_spread":0.2182829705080969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}