{"id":"W2788046162","doi":"10.3390/pharmaceutics10010013","title":"Pharmacokinetics and Drug Metabolism in Canada: The Current Landscape—A Summary of This Indispensable Special Issue","year":2018,"lang":"en","type":"editorial","venue":"Pharmaceutics","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; University of Alberta","funders":"","keywords":"Pharmacokinetics; Drug metabolism; Drug; Current (fluid); Pharmacology; Medicine; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002791513,0.001195264,0.00167405,0.0004436457,0.0003774748,0.00007565055,0.001802475,0.000725735,0.005669457],"category_scores_gemma":[0.000420855,0.001010212,0.0002563556,0.0008334909,0.00079478,0.0001551911,0.001000597,0.006508526,0.0001114684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003959153,"about_ca_system_score_gemma":0.004772969,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.04447024,"about_ca_topic_score_gemma":0.1301838,"domain_scores_codex":[0.9923967,0.00155461,0.001815403,0.001111131,0.00156239,0.001559754],"domain_scores_gemma":[0.9941119,0.002694689,0.00109565,0.0007059697,0.0006689815,0.0007228232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005367927,0.000303381,0.001069094,0.0005357108,0.0004814196,0.00006195979,0.001098517,0.000144521,0.0004817763,0.00003232159,0.9317883,0.06346625],"study_design_scores_gemma":[0.00449378,0.00002360459,0.0001509778,0.0001080281,0.001923222,0.000006661106,0.0001077028,0.002540671,0.01304431,0.0001644228,0.9764553,0.0009812873],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.01252644,0.08074811,0.000002218381,0.0009437063,0.886206,0.001516965,0.004163623,0.00004835792,0.01384454],"genre_scores_gemma":[0.01058576,0.1465722,0.00006147408,0.001305186,0.8377903,0.0001317593,0.0004836508,0.0002091638,0.002860495],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.0857136,"threshold_uncertainty_score":0.9992348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04818841988891613,"score_gpt":0.3908759117886192,"score_spread":0.342687491899703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}