{"id":"W2788205072","doi":"10.1091/mbc.e17-08-0531","title":"The nonmotor adaptor HMMR dampens Eg5-mediated forces to preserve the kinetics and integrity of chromosome segregation","year":2018,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Biology; Chromosome segregation; Signal transducing adaptor protein; Cell biology; Mitosis; Anaphase; Kinetochore; Gene silencing; Spindle pole body; Kinesin; Spindle apparatus; Microtubule; Cell division; Genetics; Cell; Chromosome; Cell cycle; Phosphorylation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001525181,0.0005337839,0.0002836348,0.0001481717,0.0001119341,0.0003521869,0.0003898314,0.0003105172,0.001612792],"category_scores_gemma":[0.000104949,0.0001721832,0.0002303817,0.00007507289,0.0002193425,0.0002381878,0.0004174055,0.0004954306,0.000630084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003528383,"about_ca_system_score_gemma":0.0001722631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003974015,"about_ca_topic_score_gemma":0.0008802325,"domain_scores_codex":[0.9998337,0.00001446089,0.00001726354,0.00005008193,0.00004771347,0.00003680982],"domain_scores_gemma":[0.9998978,0.00001394878,0.00004060036,0.00001784377,0.000007748802,0.00002196825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002683506,0.000005937213,0.00007263212,0.00002196248,0.000002565309,0.00002350429,0.000002439378,0.00002991498,0.999254,0.00003964577,0.00001105429,0.0005093704],"study_design_scores_gemma":[0.00000788427,0.00005474579,0.003464276,0.000004604357,0.00001041399,0.0001235094,0.000008566606,0.0008033899,0.9941407,0.00001422197,0.001365111,0.000002543415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909537,0.002128985,0.004964435,0.00008604907,0.00002574384,0.00001943558,0.0002329528,0.0002856431,0.001303078],"genre_scores_gemma":[0.9932673,0.0006240275,0.002462007,0.00004985414,0.000006881823,0.00001948193,0.0003542753,0.00003990629,0.003176247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001612792,"threshold_uncertainty_score":0.005395293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006647651148240255,"score_gpt":0.2376608216006152,"score_spread":0.2310131704523749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}