{"id":"W2788351363","doi":"10.1016/j.humpath.2018.02.014","title":"Familial PDGFRA -mutation syndrome: somatic and gastrointestinal phenotype","year":2018,"lang":"en","type":"article","venue":"Human Pathology","topic":"Gastrointestinal Tumor Research and Treatment","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Royal Columbian Hospital; Kingston General Hospital; Queen's University","funders":"","keywords":"PDGFRA; Germline mutation; Germline; GiST; Mutation; Biology; Gastrointestinal tract; Stromal tumor; Phenotype; Somatic cell; Pathology; Cancer research; Medicine; Stromal cell; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001379382,0.0001341495,0.0002236544,0.0001191247,0.0001493141,0.00001484501,0.00004744787,0.00002458986,0.000296311],"category_scores_gemma":[0.0001663995,0.0001123605,0.00003597071,0.00007695836,0.000425352,0.00004043935,0.00005194784,0.0001516889,0.000341932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004508132,"about_ca_system_score_gemma":0.00004892279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002158,"about_ca_topic_score_gemma":0.00002152302,"domain_scores_codex":[0.9989839,0.00006446986,0.0001827756,0.0002705942,0.000156376,0.000341875],"domain_scores_gemma":[0.9994295,0.00004323605,0.00005267999,0.0001950914,0.00009611004,0.0001834474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009839851,0.001315169,0.7410712,0.0004760776,0.0001005038,0.07337081,0.001077902,7.988702e-7,0.1642503,0.008169735,0.001218842,0.007964695],"study_design_scores_gemma":[0.001966375,0.01069246,0.8799815,0.0001650788,0.00006216337,0.1028517,0.0001120197,0.0001206795,0.0005038874,0.003424965,0.00002807575,0.00009106245],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961643,0.00004374726,0.0006067296,0.000326163,0.00003478134,0.0002718544,0.000004083209,0.00007118809,0.002477122],"genre_scores_gemma":[0.9898461,0.00000126394,0.009365281,0.0001160507,0.0001263241,0.00002192102,0.00003345285,0.0000175916,0.0004720398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1637464,"threshold_uncertainty_score":0.4581926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02730551950192405,"score_gpt":0.3157167928941242,"score_spread":0.2884112733922002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}