{"id":"W2788794199","doi":"10.1039/c8ob00316e","title":"Synthetic polyprenol-pyrophosphate linked oligosaccharides are efficient substrates for mycobacterial galactan biosynthetic enzymes","year":2018,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; Alberta Hospital Edmonton; University of Alberta","funders":"NIH Clinical Center; Canadian Glycomics Network; Natural Sciences and Engineering Research Council of Canada; Alberta Glycomics Centre; Naito Foundation","keywords":"Chemistry; Pyrophosphate; Galactan; Enzyme; Biochemistry; Glycosyltransferase; Pyrophosphatases; Combinatorial chemistry; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002448026,0.0008266009,0.0007211179,0.00005339713,0.0004412223,0.0002812828,0.000938581,0.0007065382,0.009202335],"category_scores_gemma":[0.000562105,0.0008464045,0.0005029167,0.0003939933,0.0006410995,0.00007040433,0.0002134826,0.0003047776,0.0001909704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002545696,"about_ca_system_score_gemma":0.000237763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000156865,"about_ca_topic_score_gemma":0.000003046859,"domain_scores_codex":[0.9962192,0.00002592492,0.0007906518,0.001369832,0.0004755016,0.00111891],"domain_scores_gemma":[0.9971113,0.000192897,0.0004815279,0.001452615,0.0003198748,0.0004418274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002408321,0.0002758492,0.00007533115,0.0007289787,0.0002043902,0.00006066412,0.0001472892,3.808375e-7,0.9978272,0.00001607204,0.0001720731,0.0002508869],"study_design_scores_gemma":[0.0009576976,0.00003315326,0.00002057207,0.0003819612,0.0002803278,0.0001154204,0.0004626711,0.0003437558,0.9949521,0.00009339984,0.00137166,0.0009872987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910833,0.001046056,0.001622376,0.0003368591,0.0003615852,0.0002246907,0.0003996089,0.0004462862,0.004479275],"genre_scores_gemma":[0.9968207,0.00005669121,0.0002555609,0.00006226323,0.00120385,0.00009513782,0.0001864168,0.0001908322,0.001128471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009011365,"threshold_uncertainty_score":0.9993986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00866361907040249,"score_gpt":0.2142115602432288,"score_spread":0.2055479411728263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}