{"id":"W2789017398","doi":"10.1038/nrclinonc.2018.27","title":"Cancer immunotherapy and the value of cure","year":2018,"lang":"en","type":"review","venue":"Nature Reviews Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":188,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Immunotherapy; Oncology; Cancer immunotherapy; Clinical Oncology; Cancer; Internal medicine; Value (mathematics); Immune checkpoint; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.007439287,0.0005249784,0.008598207,0.00009950478,0.00005728,0.00000949315,0.0004674155,0.003145421,0.0002735117],"category_scores_gemma":[0.001161215,0.0002306798,0.003158126,0.0004788561,0.002032495,0.00002664132,0.0001093734,0.003223932,0.00002336571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000187818,"about_ca_system_score_gemma":0.001612728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004251171,"about_ca_topic_score_gemma":0.00002895894,"domain_scores_codex":[0.9927067,0.002666874,0.003442171,0.000630089,0.0002527573,0.0003014705],"domain_scores_gemma":[0.9927647,0.003246092,0.002707204,0.0009819702,0.0001763982,0.0001236407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001566974,0.0001533043,0.00001606881,0.01076131,0.001382044,0.000006172561,0.00002570986,9.451395e-10,2.749451e-7,0.0003908119,0.03241815,0.9532792],"study_design_scores_gemma":[0.004965538,0.001004092,0.00005120675,0.0241861,0.00369971,0.0001486072,0.000002748706,6.785884e-7,2.227026e-7,0.00006304445,0.965668,0.0002100944],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000003954175,0.9900198,0.000003730615,0.002660449,0.002339001,0.003666047,0.0000282162,0.00002905967,0.00124976],"genre_scores_gemma":[0.000001053761,0.989523,0.0004976654,0.006703329,0.002081458,0.0003638338,0.00002614592,0.00008348865,0.0007200448],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9530691,"threshold_uncertainty_score":0.9990757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1248919990817849,"score_gpt":0.5402313480486471,"score_spread":0.4153393489668623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}