{"id":"W2789089340","doi":"10.1021/acs.langmuir.8b00338","title":"Microfluidic Assembly To Synthesize Dual Enzyme/Oxidation-Responsive Polyester-Based Nanoparticulates with Controlled Sizes for Drug Delivery","year":2018,"lang":"en","type":"article","venue":"Langmuir","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Precision Nanosystems (Canada); Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Microfluidics; Chemistry; Nanocarriers; Drug delivery; Nanotechnology; Polymer; Colloid; Controlled release; Chemical engineering; Materials science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007796187,0.0003489445,0.0005603032,0.0001846171,0.0003678588,0.0002270955,0.0003226384,0.00008749157,0.0002695305],"category_scores_gemma":[0.0004443209,0.000269172,0.000128051,0.0003305812,0.0002272172,0.0002981026,0.00007251621,0.00006377662,0.0009593595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001080887,"about_ca_system_score_gemma":0.0002815497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001741977,"about_ca_topic_score_gemma":0.0001539795,"domain_scores_codex":[0.9974,0.0002705512,0.0004789814,0.0006318907,0.0004237953,0.000794723],"domain_scores_gemma":[0.9968991,0.001608084,0.0002018746,0.0004902338,0.0005484386,0.0002523062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00634537,0.0001654239,0.000232665,0.00002966238,0.00003855592,0.00002735596,0.0005442951,0.00003369696,0.9814011,0.00009554043,0.01095546,0.0001309011],"study_design_scores_gemma":[0.00537759,0.0006296629,0.0006890593,0.00008991614,0.0001381512,0.000009557023,0.0002285466,0.0003747041,0.9882836,0.00002986304,0.003739298,0.0004100535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937446,0.0005153375,0.00118961,0.002355608,0.0003228433,0.00142807,0.0001192197,0.0002739784,0.00005072159],"genre_scores_gemma":[0.9929312,0.000003279572,0.003407381,0.002368233,0.0003442634,0.0004542666,0.00001838221,0.00006411538,0.000408835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007216166,"threshold_uncertainty_score":0.999976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01107895348483228,"score_gpt":0.2421867208394425,"score_spread":0.2311077673546102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}