{"id":"W2789324586","doi":"10.1007/978-1-4939-7780-2_20","title":"Correlative Live Imaging and Immunofluorescence for Analysis of Chromosome Segregation in Mouse Preimplantation Embryos","year":2018,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Chromothripsis; Biology; Micronucleus test; Centromere; Genetics; Chromosome segregation; Embryo; Chromosome; Cell biology; Genome instability; DNA; DNA damage; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005724329,0.00007543463,0.0002859478,0.0003483323,0.00001562037,0.000002927924,0.00004315117,0.00008117341,0.000005788125],"category_scores_gemma":[0.001685663,0.00006886203,0.00004286991,0.0003740825,0.0001565136,0.00002524707,0.00003370782,0.00008470358,4.096891e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003152346,"about_ca_system_score_gemma":0.00002452637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003410168,"about_ca_topic_score_gemma":0.00005115222,"domain_scores_codex":[0.9990913,0.0003135061,0.0002326622,0.0001983051,0.00003702328,0.0001271871],"domain_scores_gemma":[0.9990202,0.0006411468,0.0001003673,0.0001233447,0.0000899998,0.00002494787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002648133,0.00004273772,0.1678668,0.00002864313,0.0001478123,0.000008506923,0.0009470846,0.00006682335,0.7849059,0.001368588,0.000001934932,0.04435029],"study_design_scores_gemma":[0.002039084,0.0007349125,0.182952,0.0001453424,0.0005717239,0.00002106468,0.0003489007,0.1531457,0.6555867,0.004258754,0.00001736432,0.0001785265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3906075,0.0003554091,0.6086987,0.00003281157,0.00002824486,0.0001954823,0.00001892293,0.000006027106,0.00005689171],"genre_scores_gemma":[0.5606282,0.00002948921,0.4391569,0.00006397133,0.000007197754,0.00002113909,0.0000797714,0.000004629422,0.000008712919],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.1700206,"threshold_uncertainty_score":0.2808112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02477465206157291,"score_gpt":0.4023170454941825,"score_spread":0.3775423934326095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}