{"id":"W2789334038","doi":"10.1093/jcag/gwy009.085","title":"A85 SEMAPHORIN-3E AMELIORATES INTESTINAL INFLAMMATION BY REGULATING EXPRESSION OF TIGHT JUNCTION PROTEIN AND PROINFLAMMATORY MEDIATORS","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Medicinal Plants and Bioactive Compounds","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Semaphorin; Plexin; Proinflammatory cytokine; Wound healing; Immune system; Ulcerative colitis; Colitis; Inflammation; Tumor necrosis factor alpha; Immunofluorescence; Immunology; Chemistry; Receptor; Andrology; Cancer research; Biology; Pathology; Medicine; Internal medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006549068,0.00008029481,0.000171473,0.00009911636,0.00007427994,0.00000794171,0.0001192801,0.0001096319,0.000008331182],"category_scores_gemma":[0.0004649258,0.0000579052,0.00005107899,0.00005368028,0.0001141772,0.00001272887,0.00003099976,0.0001198656,2.173674e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001191118,"about_ca_system_score_gemma":0.0001751226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003273621,"about_ca_topic_score_gemma":0.01283282,"domain_scores_codex":[0.999001,0.0001872115,0.0003910242,0.00008667231,0.0001912037,0.0001428701],"domain_scores_gemma":[0.9980652,0.00001657359,0.001259349,0.00008540037,0.000477749,0.00009568133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002408559,0.000007143724,0.2536139,0.00001505458,0.00003659621,4.100276e-7,0.00005325321,0.00000245513,0.7421257,0.000006270064,0.003632981,0.0002654295],"study_design_scores_gemma":[0.001390559,0.002248968,0.1674339,0.0002510273,0.0000576761,0.00008533397,0.0001973946,0.00005705521,0.8234187,0.0001202549,0.004653644,0.00008548197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981248,0.00002751038,0.0001064214,0.001327182,0.0002331383,0.0001079454,0.00001022308,9.289615e-7,0.0000618331],"genre_scores_gemma":[0.999122,0.000009467977,0.0002581622,0.00006496768,0.000400031,0.000001641017,0.000008860166,0.000005836321,0.0001290639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0861799,"threshold_uncertainty_score":0.7161017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004337332863856596,"score_gpt":0.2010607846285515,"score_spread":0.1967234517646949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}