{"id":"W2789334038","doi":"10.1093/jcag/gwy009.085","title":"A85 SEMAPHORIN-3E AMELIORATES INTESTINAL INFLAMMATION BY REGULATING EXPRESSION OF TIGHT JUNCTION PROTEIN AND PROINFLAMMATORY MEDIATORS","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Medicinal Plants and Bioactive Compounds","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Semaphorin; Plexin; Proinflammatory cytokine; Wound healing; Immune system; Ulcerative colitis; Colitis; Inflammation; Tumor necrosis factor alpha; Immunofluorescence; Immunology; Chemistry; Receptor; Andrology; Cancer research; Biology; Pathology; Medicine; Internal medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001520846,0.0003007379,0.0004891938,0.0003900649,0.000121435,0.0002240894,0.0002097347,0.0003540095,0.002077018],"category_scores_gemma":[0.00009979348,0.0001560181,0.000372729,0.0001864046,0.0002067512,0.0002451665,0.000180977,0.001217272,0.0003223594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001530274,"about_ca_system_score_gemma":0.0003104441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004722819,"about_ca_topic_score_gemma":0.0009982541,"domain_scores_codex":[0.9998631,0.00001948853,0.00001606619,0.0000173777,0.00004052387,0.00004337401],"domain_scores_gemma":[0.9999268,0.000005522311,0.0000213064,0.000007146136,0.00001088789,0.00002831073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003565707,0.001215304,0.0005503841,0.0004172206,0.00007509258,0.00008246001,0.00003225718,0.0002580108,0.9795742,0.0002053813,0.0006433627,0.0133806],"study_design_scores_gemma":[0.001109916,0.01697762,0.023891,0.0001310946,0.0003063442,0.0005182044,0.0002103289,0.003112033,0.9370233,0.0004353572,0.01625757,0.00002726867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874534,0.00650383,0.001692553,0.000375212,0.0001980722,0.00008914943,0.0007599757,0.0003894266,0.00253838],"genre_scores_gemma":[0.9882013,0.00361596,0.001555772,0.0002414235,0.00003857419,0.00008621281,0.001042058,0.00002767573,0.005191124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002077018,"threshold_uncertainty_score":0.006948292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004337332863856596,"score_gpt":0.2010607846285515,"score_spread":0.1967234517646949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}