{"id":"W2789402564","doi":"10.1038/s41598-018-22283-z","title":"Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Trace Elements in Health","field":"Nursing","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Journal of Gastroenterology and Hepatology Foundation","keywords":"Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000387691,0.0005452587,0.0003467814,0.0002431234,0.0001471216,0.000256179,0.0002829506,0.0006060333,0.00139974],"category_scores_gemma":[0.0005723878,0.0001744942,0.0005950392,0.0001998739,0.0005674671,0.0001967638,0.0003061082,0.0007381249,0.0005145199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001412848,"about_ca_system_score_gemma":0.0001598304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003297451,"about_ca_topic_score_gemma":0.0004613734,"domain_scores_codex":[0.9996655,0.0001120855,0.00005197375,0.00006802585,0.00006633093,0.00003603136],"domain_scores_gemma":[0.9995174,0.0001089918,0.0002277542,0.00006133395,0.00002384317,0.00006073252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000724103,0.0001365897,0.004375523,0.00006227168,0.0000898425,0.001314362,0.00006175745,0.0006114813,0.9875235,0.0004659948,0.0000890497,0.004545612],"study_design_scores_gemma":[0.0005427491,0.003947594,0.05042481,0.00005833424,0.00033184,0.01885106,0.0002025149,0.00638786,0.9125366,0.00129976,0.005315671,0.0001014102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940476,0.000529129,0.004626243,0.0001146311,0.0000329987,0.00002924621,0.0002588457,0.00006013508,0.0003011963],"genre_scores_gemma":[0.9963545,0.0001532896,0.002934653,0.0000728883,0.00001244502,0.000007279462,0.0002160353,0.00002815948,0.0002206336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00139974,"threshold_uncertainty_score":0.004682541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04915091651330308,"score_gpt":0.3389645497560902,"score_spread":0.2898136332427871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}