{"id":"W2789435700","doi":"10.1111/imcb.12033","title":"TCR deep sequencing of transgenic RAG‐1‐deficient mice reveals endogenous TCR recombination: a cause for caution","year":2018,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Health and Medical Research Council","keywords":"T-cell receptor; Transgene; Genetically modified mouse; Biology; Endogeny; Gene knockout; Knockout mouse; Molecular biology; Cell biology; Gene; T cell; Genetics; Biochemistry; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001447451,0.0002959706,0.0003391758,0.0004037166,0.0004447749,0.0009153386,0.0004397461,0.0007406048,0.00129],"category_scores_gemma":[0.001248398,0.0002572464,0.0002392193,0.0002876409,0.0008038335,0.0005135412,0.0004386893,0.001673876,0.0007575073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002069741,"about_ca_system_score_gemma":0.0003140886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005449937,"about_ca_topic_score_gemma":0.002354243,"domain_scores_codex":[0.9994,0.0001571761,0.00006438528,0.0001378673,0.0001762948,0.00006431053],"domain_scores_gemma":[0.9989988,0.0003444946,0.0001416736,0.0002743266,0.0001335824,0.0001070446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006740026,0.00001167272,0.001044765,0.00009949692,0.00001741156,0.0002300649,0.00008134972,0.0001741509,0.9886416,0.00118966,0.0008193699,0.007623108],"study_design_scores_gemma":[0.00002396091,0.0001692095,0.01776221,0.0001322549,0.00006512357,0.003823021,0.0002103149,0.004364096,0.9325747,0.005186116,0.03566126,0.00002781063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6284741,0.006220314,0.3443985,0.004137591,0.0006026343,0.0001746622,0.003631836,0.002623577,0.0097368],"genre_scores_gemma":[0.7827183,0.004229529,0.1980132,0.003901461,0.00009181847,0.0003410885,0.002337992,0.001708309,0.006658312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001447451,"threshold_uncertainty_score":0.007654965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02413831836037566,"score_gpt":0.2344026431052416,"score_spread":0.2102643247448659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}