{"id":"W2789435700","doi":"10.1111/imcb.12033","title":"TCR deep sequencing of transgenic RAG‐1‐deficient mice reveals endogenous TCR recombination: a cause for caution","year":2018,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Health and Medical Research Council","keywords":"T-cell receptor; Transgene; Genetically modified mouse; Biology; Endogeny; Gene knockout; Knockout mouse; Molecular biology; Cell biology; Gene; T cell; Genetics; Biochemistry; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001412706,0.001026076,0.00173317,0.0007497292,0.001261893,0.00003759635,0.001104017,0.002957343,0.0001166081],"category_scores_gemma":[0.001193826,0.0009842914,0.0005014451,0.0006597891,0.003399865,0.000235919,0.0003911865,0.001275335,0.0005462659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002495766,"about_ca_system_score_gemma":0.0003927593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004000507,"about_ca_topic_score_gemma":0.0001921905,"domain_scores_codex":[0.9926027,0.001496883,0.001739268,0.001704637,0.00009270765,0.002363789],"domain_scores_gemma":[0.9926904,0.004148538,0.001187127,0.001111182,0.0007451664,0.0001176052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000111997,0.0006295833,0.0009554236,0.0001694511,0.001120065,0.00001946683,0.005253509,0.000009699138,0.9838624,0.003735636,0.002114563,0.00201822],"study_design_scores_gemma":[0.005998635,0.004486236,0.0007938138,0.00006764076,0.0005325701,0.001033307,0.004679344,0.00003271465,0.8875841,0.003491681,0.09109561,0.0002042794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9420586,0.04371338,0.001864493,0.0001161851,0.004248625,0.001488714,0.0002953074,0.0002798703,0.005934836],"genre_scores_gemma":[0.9836118,0.004149308,0.0003900201,0.0004698515,0.0001881816,0.0003223112,0.0009091398,0.0001063061,0.009853086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09627822,"threshold_uncertainty_score":0.9993123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02413831836037566,"score_gpt":0.2344026431052416,"score_spread":0.2102643247448659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}