{"id":"W2789444788","doi":"10.1093/annonc/mdy047.014","title":"Epigenetic regulation of tumor metabolism","year":2018,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Toronto General Hospital; University of Toronto","funders":"","keywords":"Epigenetics; Biology; Reprogramming; Warburg effect; Cancer cell; Population; Cancer research; Chromatin; Cancer stem cell; Cell biology; Carcinogenesis; Transcription factor; Cancer; Stem cell; Genetics; Cell; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002021383,0.0001662834,0.0001424713,0.0003048463,0.0002017686,0.0006438731,0.0002070835,0.0002790257,0.001616758],"category_scores_gemma":[0.0002147912,0.0001103985,0.0001317462,0.0002335793,0.0002952683,0.0003374401,0.0003609286,0.0004129327,0.0003411766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000361975,"about_ca_system_score_gemma":0.0002497525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002859511,"about_ca_topic_score_gemma":0.0005727248,"domain_scores_codex":[0.9999216,0.00002017543,0.000004421775,0.00001585794,0.00002182194,0.00001614513],"domain_scores_gemma":[0.9999253,0.00001380326,0.00001864442,0.00001178372,0.00001685039,0.00001373325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004660786,0.0001144109,0.01113224,0.0003182909,0.000110022,0.001226408,0.0003404306,0.001621027,0.7180014,0.06712175,0.006060896,0.1934871],"study_design_scores_gemma":[0.0000498899,0.000398997,0.0764728,0.0001444554,0.0001435459,0.003160664,0.0005331301,0.004480832,0.608152,0.04911123,0.257297,0.00005556001],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6839071,0.2038787,0.0266844,0.02235996,0.002333804,0.00004329688,0.0006930065,0.0004022896,0.05969745],"genre_scores_gemma":[0.9429138,0.03746975,0.001756003,0.0006279048,0.0005501459,0.00001335857,0.0001678519,0.00002071069,0.01648044],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001616758,"threshold_uncertainty_score":0.005408525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04556624255740941,"score_gpt":0.3576568393122999,"score_spread":0.3120905967548904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}