{"id":"W2789512244","doi":"10.1016/j.jpain.2017.12.027","title":"Loss of the sodium proton exchanger NHE6 impairs nociceptive transmission in christianson syndrome","year":2018,"lang":"en","type":"article","venue":"Journal of Pain","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Nociception; Knockout mouse; Neuroscience; Medicine; Dorsal root ganglion; Parvalbumin; Noxious stimulus; Internal medicine; Endocrinology; Sensory system; Psychology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002197586,0.0008644538,0.000484122,0.0009261487,0.0003412096,0.0002801023,0.0004634818,0.001081754,0.006289807],"category_scores_gemma":[0.0006756451,0.0002657231,0.0003845919,0.0004257094,0.001008933,0.000288288,0.0005680661,0.0006309301,0.0003900723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002641721,"about_ca_system_score_gemma":0.0003041238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001748109,"about_ca_topic_score_gemma":0.00133215,"domain_scores_codex":[0.9997665,0.00005807077,0.00004809051,0.00003700469,0.00006106415,0.00002921804],"domain_scores_gemma":[0.9995233,0.0001407788,0.0001423153,0.00003237404,0.00002119996,0.0001401225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001592136,0.00017127,0.002845221,0.0001456297,0.00009467542,0.006522171,0.0001645879,0.00059193,0.9817967,0.001015388,0.0002912284,0.004768929],"study_design_scores_gemma":[0.00126053,0.002938719,0.1173775,0.0001981214,0.0006600815,0.05476449,0.000911375,0.01211003,0.7986378,0.002289831,0.008703865,0.0001476139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978486,0.0003867341,0.0007307266,0.0001817013,0.00005239181,0.00001172706,0.0002307531,0.00006202138,0.0004952907],"genre_scores_gemma":[0.9982116,0.000322674,0.0004984869,0.0000448799,0.00001228596,0.00001071768,0.0001213482,0.00002420044,0.0007538871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006289807,"threshold_uncertainty_score":0.02104151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009798073695575569,"score_gpt":0.2463458937245283,"score_spread":0.2365478200289527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}