{"id":"W2789541411","doi":"10.1177/2045125318762365","title":"Amisulpride augmentation of clozapine for treatment-refractory schizophrenia: a double-blind, placebo-controlled trial","year":2018,"lang":"en","type":"article","venue":"Therapeutic Advances in Psychopharmacology","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University","funders":"Cilag; Health Technology Assessment Programme; H. Lundbeck A/S; Otsuka Pharmaceutical; Amicus Therapeutics; National Institute for Health and Care Research; Sunovion; Eli Lilly and Company","keywords":"Amisulpride; Clozapine; Positive and Negative Syndrome Scale; Tolerability; Placebo; Adverse effect; Medicine; Scale for the Assessment of Negative Symptoms; Internal medicine; Randomized controlled trial; Antipsychotic; Atypical antipsychotic; Schizophrenia (object-oriented programming); Psychology; Psychiatry; Psychosis; Brief Psychiatric Rating Scale","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"randomized_trial","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"randomized_trial","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004362465,0.002062959,0.004988531,0.0008283822,0.0008039108,0.001552642,0.001258653,0.003774329,0.007075079],"category_scores_gemma":[0.004753641,0.0009724967,0.003185896,0.0007204308,0.001751311,0.001251907,0.0004843527,0.002382387,0.001195052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008809617,"about_ca_system_score_gemma":0.001633067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009501876,"about_ca_topic_score_gemma":0.0018129,"domain_scores_codex":[0.9979364,0.001151229,0.0002482483,0.0003163062,0.0001722468,0.0001755452],"domain_scores_gemma":[0.997595,0.0008846406,0.0005675495,0.000241542,0.0002440007,0.000467231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9852063,0.002649781,0.000188065,0.001705026,0.001182712,0.00003611701,0.00004730633,0.00009106993,0.001838981,0.0000571487,0.0002580729,0.006739577],"study_design_scores_gemma":[0.979483,0.01914837,0.0003658066,0.00005895801,0.0004201407,0.00001622391,0.000009240526,0.0001068862,0.0001308266,0.0000430853,0.0002093269,0.000008200671],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9479499,0.0269924,0.001936858,0.001546165,0.00231935,0.01494254,0.001229771,0.0003215823,0.00276151],"genre_scores_gemma":[0.9615757,0.01217616,0.003479099,0.001729176,0.00163364,0.01486512,0.000761508,0.00004399308,0.003735516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007075079,"threshold_uncertainty_score":0.02366847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0536004326467893,"score_gpt":0.4385091208658433,"score_spread":0.384908688219054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}